Generic Name : Amiloride + Hctz
Brand Name : Moduretic
Manufacturer Name : GSK Pharma
Product Code : OBP 429
Delivery Days : 10 To 12 Working Day
Composition : Amiloride + Hctz
Strength : 5+50mg
Packaging : Tablets (Blister)
Presentation : Pills Strip
Drug Class : Diuretics
Prescribed For : Treat hypertension (high blood pressure)
Side Effects : Nausea, vomiting, diarrhea, and dehydration
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 90 TABLET'S | $30.60 | $0.34 | OUT OF STOCK |
| 60 TABLET'S | $21.00 | $0.35 | OUT OF STOCK |
| 30 TABLET'S | $10.80 | $0.36 | OUT OF STOCK |
Biduret 5+50 MG Tablets is a pharmaceutical formulation that combines two active ingredients: Amiloride hydrochloride (5 mg) and Hydrochlorothiazide (50 mg). This medication belongs to the class of combination diuretics and is commonly prescribed for the management of hypertension (high blood pressure).
Amiloride hydrochloride (5 mg):
Amiloride is a potassium-sparing diuretic.
It acts on the distal tubules of the kidneys, inhibiting the reabsorption of sodium ions. By blocking sodium channels, it reduces the exchange of sodium for potassium in the tubular cells.
This leads to increased excretion of sodium and water while sparing potassium. The net effect is a diuretic action that promotes the elimination of excess fluid without causing a significant loss of potassium.
Hydrochlorothiazide (50 mg):
Hydrochlorothiazide is a thiazide diuretic.
It works primarily in the early part of the kidney's tubules, inhibiting the reabsorption of sodium and chloride ions. This action leads to increased urine production and the elimination of excess salt and water from the body.
Thiazide diuretics are effective in reducing blood pressure by decreasing the volume of circulating blood and promoting vasodilation (widening of blood vessels).
Combined Mechanism:
The combination of Amiloride and Hydrochlorothiazide in Biduret offers a dual diuretic effect.
Amiloride's potassium-sparing action helps counteract the potential loss of potassium caused by Hydrochlorothiazide.
The diuretic effect of both components results in reduced blood volume, leading to decreased cardiac output and lower blood pressure.
Ingredients of Biduret 5+50 MG Tablets:
Amiloride hydrochloride (5 mg):
Amiloride is a potassium-sparing diuretic that works by inhibiting the reabsorption of sodium in the distal tubules of the kidneys. This results in increased excretion of sodium and water while sparing potassium.
Hydrochlorothiazide (50 mg):
Hydrochlorothiazide is a thiazide diuretic that acts on the early segments of the kidney tubules, inhibiting the reabsorption of sodium and chloride. This leads to increased urine production and the elimination of excess salt and water from the body.
Dosage Information:
The dosage of Biduret 5+50 MG Tablets is determined by the healthcare provider based on the patient's specific health condition and response to treatment.
The tablets are typically taken orally, with or without food, as directed by the healthcare professional.
Here are the main categories of individuals who may use Biduret 5+50 MG Tablets:
Hypertension Patients:
Biduret is commonly prescribed for individuals with hypertension to help control and reduce elevated blood pressure levels.
Individuals Requiring Dual Diuretic Therapy:
Biduret contains a combination of Amiloride (a potassium-sparing diuretic) and Hydrochlorothiazide (a thiazide diuretic). It is suitable for patients who may benefit from the combined effects of these two diuretics for blood pressure management.
Patients with Fluid Retention:
Biduret may be prescribed for individuals with fluid retention issues, as it promotes diuresis and helps eliminate excess salt and water from the body.
Those at Risk of Low Potassium Levels:
Amiloride, one of the components in Biduret, is potassium-sparing. This makes it suitable for individuals who are at risk of low potassium levels associated with the use of thiazide diuretics.
Patients with Specific Cardiovascular Conditions:
Healthcare providers may prescribe Biduret for individuals with certain cardiovascular conditions, as the medication's diuretic effects can contribute to overall cardiovascular health.
Individuals with Adequate Kidney Function:
Biduret is generally prescribed for individuals with adequate kidney function, as the diuretic action involves the excretion of salt and water through the kidneys.
Here are some common mistakes to avoid:
Skipping Doses:
Skipping doses can impact the effectiveness of the medication in controlling blood pressure. Follow the prescribed dosing schedule and take the medication regularly.
Double Dosing:
Do not double up on doses to make up for a missed one unless specifically advised by the healthcare provider. Taking extra doses can lead to an overdose and increase the risk of side effects.
Abrupt Discontinuation:
Do not stop taking Biduret abruptly without consulting the healthcare provider. Abrupt discontinuation can lead to a sudden increase in blood pressure.
Ignoring Side Effects:
Pay attention to any side effects and report them to the healthcare provider. Ignoring or neglecting side effects may lead to complications or the need for dosage adjustments.
Inadequate Hydration:
Diuretics, including Biduret, may increase urine production. Ensure adequate hydration to prevent dehydration, especially during hot weather or with increased physical activity.
Not Monitoring Blood Pressure:
Regularly monitor blood pressure as recommended by the healthcare provider. Failure to monitor blood pressure can result in uncontrolled hypertension.
Excessive Potassium Intake:
Avoid excessive intake of potassium-rich foods or supplements without consulting the healthcare provider. Biduret is a potassium-sparing diuretic, and additional potassium supplementation may lead to elevated levels.
Ignoring Lifestyle Modifications:
Neglecting lifestyle modifications recommended by the healthcare provider, such as dietary changes and exercise, may hinder the overall management of hypertension.
Not Informing Healthcare Provider:
Inform the healthcare provider about all medications, supplements, and herbal products being taken to avoid potential drug interactions.
Pregnancy and Breastfeeding Considerations:
Pregnant or breastfeeding individuals should not use Biduret without consulting their healthcare provider. The potential risks and benefits should be carefully evaluated.
Self-Adjusting Dosage:
Do not adjust the dosage of Biduret without consulting the healthcare provider. Dosage adjustments should be made based on professional medical advice.
Ignoring Regular Follow-Up Appointments:
Attend regular follow-up appointments with the healthcare provider. These appointments are crucial for monitoring blood pressure, assessing overall health, and adjusting the treatment plan if necessary.
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Q: What is Biduret 5+50 MG Tablets used for?
A: Biduret 5+50 MG Tablets are primarily used for the treatment of hypertension (high blood pressure). The combination of Amiloride and Hydrochlorothiazide in Biduret helps regulate blood pressure by promoting diuresis and eliminating excess salt and water from the body.
Q: How does Biduret 5+50 MG work?
A: Biduret combines a potassium-sparing diuretic (Amiloride) with a thiazide diuretic (Hydrochlorothiazide). Amiloride inhibits sodium reabsorption, promoting potassium retention, while Hydrochlorothiazide increases urine production, reducing blood volume and blood pressure.
Q: What are the common side effects of Biduret 5+50 MG Tablets?
A: Common side effects may include increased urination, dizziness, electrolyte imbalances, headache, nausea, fatigue, changes in blood urea and creatinine levels, orthostatic hypotension, and skin reactions.
Q: How should Biduret 5+50 MG Tablets be taken?
A: Biduret is usually taken orally with a full glass of water. It can be taken with or without food, as directed by the healthcare provider. Adherence to the prescribed dosage and schedule is essential for optimal effectiveness.
Q: Can Biduret 5+50 MG Tablets be taken during pregnancy?
A: Pregnant individuals should consult their healthcare provider before using Biduret. The risks and benefits of the medication during pregnancy will be carefully assessed to determine its appropriateness.
Q: Can Biduret 5+50 MG Tablets be taken while breastfeeding?
A: Breastfeeding individuals should consult their healthcare provider before using Biduret. The decision will be based on evaluating the potential risks and benefits of the medication during lactation.
Q: Can Biduret 5+50 MG Tablets cause dehydration?
A: Diuretics, including Biduret, may increase urine production and contribute to dehydration. It's important to maintain adequate hydration, especially in hot weather or during increased physical activity.
Q: How often should blood pressure be monitored while taking Biduret 5+50 MG Tablets?
A: Regular blood pressure monitoring is recommended as part of the treatment plan. The healthcare provider will determine the appropriate frequency based on individual health needs.
Q: Can Biduret 5+50 MG Tablets interact with other medications?
A: Inform your healthcare provider about all medications, supplements, and herbal products being taken, as certain substances may interact with Biduret. Adjustments to the treatment plan may be necessary.
Q: What should I do if I miss a dose of Biduret 5+50 MG Tablets?
A: If a dose is missed, take it as soon as remembered. However, if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses unless advised by the healthcare provider.
Common side effects associated with Biduret 5+50 MG Tablets may include:
Increased Urination
Dizziness
Electrolyte Imbalance
Headache
Nausea or Upset Stomach
Fatigue
Skin Reactions
Here are the main uses of Biduret 5+50 MG Tablets:
Hypertension (High Blood Pressure):
The primary and most common use of Biduret is in the management of hypertension. The combination of Amiloride and Hydrochlorothiazide provides a dual diuretic effect, helping to reduce blood pressure by increasing urine production and eliminating excess salt and water from the body.
Combination Therapy:
Biduret is prescribed when a combination of diuretics is deemed necessary to achieve optimal blood pressure control. The inclusion of Amiloride, a potassium-sparing diuretic, helps mitigate the potential loss of potassium associated with thiazide diuretics like Hydrochlorothiazide.
Fluid Retention:
Biduret may be used to address fluid retention associated with hypertension or other cardiovascular conditions. The diuretic action helps the body eliminate excess fluid, reducing swelling and edema.
Cardiovascular Risk Reduction:
By effectively controlling blood pressure, Biduret contributes to the reduction of cardiovascular risks associated with hypertension. This includes a decreased risk of heart attacks, strokes, and other cardiovascular complications.
Potassium-Sparing Effect:
Amiloride's potassium-sparing properties are beneficial for individuals who may be at risk of low potassium levels due to the use of thiazide diuretics. Biduret helps maintain a balance between sodium and potassium levels in the body.
Here are general guidelines on how to use Biduret:
1. Prescription and Dosage:
Biduret 5+50 MG Tablets should only be used as prescribed by a qualified healthcare professional.
The dosage will be determined based on the individual's health condition, response to treatment, and other relevant factors.
2. Administration:
Take Biduret 5+50 MG Tablets orally, usually with a full glass of water.
The tablets can be taken with or without food, as directed by the healthcare provider.
3. Regular Schedule:
Follow a regular schedule for taking Biduret. It is often recommended to take the medication at the same time each day to maintain consistent blood levels.
4. Do Not Skip Doses:
Adhere to the prescribed dosing schedule, and do not skip doses. If a dose is missed, take it as soon as remembered, but if it is almost time for the next dose, skip the missed dose and continue with the regular schedule.
5. Do Not Double Up:
Do not double up on doses to make up for a missed dose unless specifically advised by the healthcare provider.
6. Monitoring Blood Pressure:
Regularly monitor blood pressure as recommended by the healthcare provider. This helps assess the effectiveness of the medication in controlling hypertension.
7. Report Side Effects:
Report any side effects or concerns to the healthcare provider promptly. This includes symptoms such as dizziness, persistent headaches, changes in urination, or signs of electrolyte imbalance.
8. Follow-Up Appointments:
Attend follow-up appointments with the healthcare provider as scheduled. These appointments are essential for monitoring blood pressure, assessing overall health, and making any necessary adjustments to the treatment plan.
9. Informing Healthcare Provider:
Inform the healthcare provider about all medications, supplements, and herbal products being taken, as certain substances may interact with Biduret.
10. Pregnancy and Breastfeeding:
Pregnant or breastfeeding individuals should consult their healthcare provider before using Biduret to assess the potential risks and benefits.
11. Lifestyle Modifications:
Follow any lifestyle modifications recommended by the healthcare provider. This may include dietary changes, exercise, and other measures to complement the medication's effects.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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