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Brufen 400 MG is commonly prescribed to alleviate pain and reduce inflammation. It is often used for conditions such as osteoarthritis, rheumatoid arthritis, menstrual cramps, dental pain, and mild to moderate pain. You can buy Brufen 400 MG Tablets online in the USA/UK from Online Blue Pills at best prices.

Generic Name : Ibuprofen

Brand Name : Motrin

Manufacturer Name : Abbott

Product Code : OBP 119

Delivery Days : 10 To 12 Working Days

Composition : Ibuprofen

Strength : 400mg

Packaging : Tablet (Blisters)

Presentation : Pills Strip

Drug Class : NSAIDs

Prescribed For : Treatment of rheumatoid arthritis (including juvenile rheumatoid arthritis

Side Effects : Nausea or vomiting, Loss of appetite, Heartburn or pain in the upper part of your stomach

Pack Size/Qty Price Price Per Pill or unit  
90 TABLET'S $15.30 $0.17

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60 TABLET'S $10.80 $0.18

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30 TABLET'S $7.20 $0.24

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Descriptions

What is Brufen 400 MG Tablets?

Brufen 400 MG Tablets are a medication containing Ibuprofen as the active ingredient. Ibuprofen belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and is widely used to alleviate pain and reduce inflammation.


How does Brufen 400 MG Tablets work?

The mechanism of action of Brufen 400 MG involves several processes in the body:

Inhibition of Prostaglandin Synthesis:

Ibuprofen works by inhibiting the activity of enzymes known as cyclooxygenases (COX-1 and COX-2). These enzymes play a crucial role in the synthesis of prostaglandins, which are hormone-like substances involved in inflammation, pain, and fever.
Reduction of Prostaglandin Levels:

Prostaglandins are signaling molecules that contribute to the inflammatory response in the body. They promote vasodilation, increase vascular permeability, and sensitize nerve endings to pain. By inhibiting COX enzymes, Ibuprofen reduces the production of prostaglandins.
Anti-Inflammatory Effects:

By decreasing prostaglandin levels, Brufen 400 MG exerts anti-inflammatory effects. Inflammation is a complex biological response to injury or infection, and the reduction of prostaglandins helps alleviate swelling, redness, and pain associated with inflammatory conditions such as arthritis.
Analgesic (Pain-Relieving) Effects:

Ibuprofen's ability to reduce prostaglandin levels results in pain relief. Prostaglandins sensitize nerve endings to pain, and by inhibiting their production, Brufen 400 MG helps mitigate pain signals, making it effective in managing various types of pain, including musculoskeletal pain and dental pain.
Antipyretic Effects:

Prostaglandins also play a role in regulating body temperature and inducing fever during an inflammatory response. By lowering prostaglandin levels, Brufen 400 MG helps reduce fever, making it useful in managing febrile conditions.
Vasoconstriction in the Kidneys:

Ibuprofen may cause vasoconstriction in the kidneys, leading to a reduction in blood flow. This effect is thought to contribute to the drug's ability to reduce inflammation in certain conditions.


Ingredients and dosages Brufen 400 MG Tablets

Ingredients and Dosages of Brufen 400 MG Tablets:

1. Active Ingredient:

Each Brufen 400 MG Tablet contains 400 milligrams of Ibuprofen.

2. Inactive Ingredients:

Inactive ingredients may vary among different formulations and brands of Ibuprofen. Common inactive ingredients include microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate, and others. These components are used for various purposes such as binding the tablet, enhancing stability, and facilitating absorption.


Who can use Brufen 400 MG Tablets?

However, there are certain considerations regarding who can safely use Brufen 400 MG Tablets:

Adults:

Brufen 400 MG Tablets are generally intended for use in adults. The dosage and administration guidelines provided by a healthcare professional should be followed strictly.
Health Conditions:

Individuals with certain health conditions may need special consideration before using Brufen 400 MG Tablets. It is important to consult a healthcare provider before use, especially if you have:
Gastrointestinal disorders (e.g., ulcers, bleeding disorders)
Cardiovascular diseases (e.g., heart disease, hypertension)
Renal impairment or kidney disease
Liver disease
Asthma or other respiratory conditions
Allergies to NSAIDs (nonsteroidal anti-inflammatory drugs)
Pregnancy and Breastfeeding:

Pregnant or breastfeeding individuals should consult their healthcare provider before using Brufen 400 MG Tablets. The potential risks and benefits should be evaluated, and alternative treatment options may be considered.
Elderly Individuals:

Elderly individuals may be more susceptible to certain side effects of Brufen 400 MG Tablets, such as gastrointestinal bleeding or renal impairment. Lower doses or closer monitoring may be necessary in this population.
Children:

Brufen 400 MG Tablets are not typically recommended for use in children unless specifically prescribed by a healthcare provider. Alternative formulations or dosages may be more suitable for pediatric patients.
Medication Interactions:

Individuals taking other medications, including prescription drugs, over-the-counter medications, and supplements, should consult their healthcare provider before using Brufen 400 MG Tablets. Certain medications may interact with Ibuprofen and require dosage adjustments or monitoring.
Allergic Reactions:

Individuals with a known allergy to Ibuprofen or other NSAIDs should avoid using Brufen 400 MG Tablets. Allergic reactions may include rash, itching, swelling, difficulty breathing, or anaphylaxis, and immediate medical attention should be sought if such reactions occur.


Common mistakes to avoid Brufen 400 MG Tablets

Here are some key points to avoid:

Exceeding the Prescribed Dosage:

Avoid taking more Brufen 400 MG Tablets than prescribed by your healthcare provider. Exceeding the recommended dosage can increase the risk of side effects and complications.
Skipping Doses:

Do not skip doses of Brufen 400 MG. Consistent adherence to the prescribed schedule is crucial for maintaining a steady level of the medication in your system.
Not Taking with Food or Milk:

To reduce the risk of stomach upset, it is recommended to take Brufen 400 MG Tablets with food or milk. Skipping this step may increase the likelihood of gastrointestinal side effects.
Crushing or Chewing Tablets:

Do not crush or chew Brufen 400 MG Tablets unless your healthcare provider specifically advises you to do so. Swallow the tablet whole with a glass of water to ensure proper absorption.
Consuming Alcohol:

Avoid or limit alcohol intake while taking Brufen 400 MG. Alcohol can increase the risk of gastrointestinal side effects and may interact with the medication.
Ignoring Allergic Reactions:

Pay attention to any signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing. If you experience these symptoms, seek immediate medical attention and discontinue the medication.
Long-Term Use without Monitoring:

Do not use Brufen 400 MG Tablets for an extended period without regular monitoring by your healthcare provider. Prolonged use may increase the risk of side effects, particularly on the gastrointestinal and cardiovascular systems.
Not Informing Healthcare Provider of Other Medications:

Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions with Brufen 400 MG.
Ignoring Pre-existing Conditions:

If you have pre-existing health conditions such as gastrointestinal issues, cardiovascular problems, or kidney disease, inform your healthcare provider before starting Brufen 400 MG. Ignoring these conditions may exacerbate potential risks.
Not Seeking Medical Attention for Side Effects:

If you experience persistent or severe side effects, such as gastrointestinal bleeding, black stools, or changes in kidney function, seek immediate medical attention. Ignoring serious side effects can lead to complications.
Self-Medication:

Do not self-medicate with Brufen 400 MG. Always consult your healthcare provider for an accurate diagnosis and appropriate treatment plan.


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Faq

FAQs on Brufen 400 MG Tablets

Q: What is Brufen 400 MG used for?


A: Brufen 400 MG Tablets contain Ibuprofen and are used to relieve pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, menstrual cramps, dental pain, and various inflammatory disorders.


Q: How does Brufen 400 MG work?


A: Brufen 400 MG works by inhibiting the production of prostaglandins, substances in the body that contribute to inflammation, pain, and fever. By reducing prostaglandin levels, it provides relief from pain and inflammation.


Q: Can I take Brufen 400 MG on an empty stomach?


A: While Brufen 400 MG can be taken on an empty stomach, it is recommended to take it with food or milk to minimize the risk of stomach upset.


Q: How often can I take Brufen 400 MG?


A: The dosage frequency is typically every 4 to 6 hours, as needed for pain or inflammation. However, the specific dosing schedule will be determined by your healthcare provider based on your medical condition.


Q: Can Brufen 400 MG be taken during pregnancy?


A: Pregnant individuals should consult their healthcare provider before using Brufen 400 MG. It may be prescribed in certain situations, but the potential risks and benefits should be carefully evaluated.


Q: Can I drink alcohol while taking Brufen 400 MG?


A: It is advisable to limit or avoid alcohol consumption while taking Brufen 400 MG. Alcohol can increase the risk of gastrointestinal side effects.


Q: Are there any interactions with other medications?


A: Brufen 400 MG may interact with certain medications, including other NSAIDs, blood thinners, and some antihypertensive drugs. Inform your healthcare provider about all medications and supplements you are taking.


Q: What should I do if I miss a dose of Brufen 400 MG?


A: If you miss a dose, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with the regular dosing schedule. Do not double up to make up for a missed dose.


Q: Can I use Brufen 400 MG for a prolonged period?


A: Prolonged use of Brufen 400 MG should be under the supervision of a healthcare provider. Regular monitoring is necessary to assess potential side effects and ensure its continued safety and effectiveness.


Q: What are the common side effects of Brufen 400 MG?


A: Common side effects may include gastrointestinal discomfort, nausea, headache, dizziness, and fluid retention. If any side effects persist or worsen, contact your healthcare provider.

Side Effect

Common side effects of Brufen 400 MG Tablets

Common side effects of Brufen 400 MG Tablets may include:

Gastrointestinal Discomfort:

Mild to moderate stomach discomfort, indigestion, or abdominal pain may occur. Taking the medication with food or milk can help alleviate these symptoms.
Nausea and Vomiting:

Some individuals may experience nausea and, in rare cases, vomiting. If persistent, it's advisable to inform your healthcare provider.
Headache:

Headache is a common side effect that usually resolves on its own. If headaches persist or become severe, consult your healthcare provider.
Dizziness:

Brufen 400 MG may cause dizziness. Avoid activities that require mental alertness, such as driving, until you know how the medication affects you.
Fluid Retention:

Some individuals may experience mild fluid retention, leading to swelling in the ankles or hands. If this becomes bothersome, inform your healthcare provider.
High Blood Pressure:

Ibuprofen, the active ingredient in Brufen 400 MG, can, in some cases, lead to an increase in blood pressure. Regular monitoring may be necessary for individuals with hypertension.
Skin Rash:

Skin reactions, including rash or itching, may occur. If you notice any skin changes, consult your healthcare provider, especially if they are severe or accompanied by other symptoms.
Constipation or Diarrhea:

Changes in bowel habits, such as constipation or diarrhea, may occur. Staying hydrated and maintaining a balanced diet can help manage these effects.
Elevated Liver Enzymes:

In some cases, Brufen 400 MG may cause a temporary increase in liver enzymes. Regular monitoring by your healthcare provider is essential.
Heartburn:

Heartburn or mild discomfort in the chest area may occur. Taking the medication with food can help reduce the risk of heartburn.
Allergic Reactions:

While rare, severe allergic reactions can occur. Seek immediate medical attention if you experience difficulty breathing, swelling, severe rash, or other signs of a serious allergic reaction.

Uses

Uses of Brufen 400 MG Tablets

Here are some common uses:

Pain Management:

Brufen 400 MG is used to relieve mild to moderate pain associated with conditions such as:
Musculoskeletal pain
Dental pain
Headaches
Menstrual cramps
Inflammatory Conditions:

Brufen 400 MG is effective in managing inflammatory conditions, including:
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis
Juvenile idiopathic arthritis
Fever Reduction:

The antipyretic properties of Brufen 400 MG make it suitable for reducing fever associated with various illnesses.
Postoperative Pain:

Following surgical procedures, Brufen 400 MG may be prescribed to manage postoperative pain and inflammation.
Soft Tissue Injuries:

Injuries such as strains, sprains, or sports-related injuries that involve inflammation and pain can be alleviated with Brufen 400 MG.
Dysmenorrhea (Menstrual Pain):

Women experiencing menstrual cramps and discomfort may find relief with Brufen 400 MG.
Bursitis and Tendinitis:

Conditions involving inflammation of the bursae (bursitis) or tendons (tendinitis) may benefit from the anti-inflammatory effects of Brufen 400 MG.
Dental Procedures:

Pain and inflammation resulting from dental procedures, such as tooth extraction or dental surgery, can be managed with Brufen 400 MG.
Migraine Headaches:

For some individuals suffering from migraine headaches, Brufen 400 MG may be recommended as part of a treatment plan.
Fever Associated with Infections:

Brufen 400 MG can be used to reduce fever caused by various infections, helping to improve comfort and facilitate recovery.


How to use Brufen 400 MG Tablets?

Here are general instructions for using Brufen 400 MG Tablets:

Dosage Instructions:

Take Brufen 400 MG Tablets exactly as prescribed by your healthcare provider. Do not self-adjust the dosage without consulting your doctor.
Administration with Food or Milk:

To minimize the risk of stomach upset, it is advisable to take Brufen 400 MG Tablets with food or milk. This can help protect the stomach lining.
Swallow Whole with Water:

Swallow the tablet whole with a glass of water. Do not crush, break, or chew the tablet, unless your healthcare provider advises otherwise. Breaking or crushing the tablet may alter its release mechanism.
Regular Intervals:

Take Brufen 400 MG Tablets at regular intervals as prescribed. This is typically every 4 to 6 hours, depending on the severity of your pain or inflammation.
Avoid Alcohol:

It's advisable to limit or avoid alcohol consumption while taking Brufen 400 MG. Alcohol may increase the risk of gastrointestinal side effects.
Missed Dose:

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double up to make up for a missed dose.
Overdose Concerns:

If you suspect an overdose or experience symptoms such as nausea, vomiting, stomach pain, drowsiness, or black stools, seek immediate medical attention.
Regular Monitoring:

Attend regular check-ups with your healthcare provider to monitor your response to the medication and address any concerns or side effects.
Long-Term Use:

If you are prescribed Brufen 400 MG for an extended period, your healthcare provider will closely monitor your health, especially if you have pre-existing conditions.
Individualized Instructions:

Your healthcare provider may provide additional instructions based on your specific health condition, age, and other factors. Always follow their guidance for the best results.

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Disclaimer

The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.

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