Generic Name : Gefitinib
Brand Name : Iressa
Manufacturer Name : Natco Pharma
Product Code : OBP 1040
Delivery Days : 10 To 12 Working Days
Composition : Gefitinib
Strength : 250mg
Packaging : Tablet (Blisters)
Presentation : Pills Strip
Drug Class : Abdominal or stomach pain or tenderness, clay colored stools, decreased appetite, diarrhea, severe, itching or skin rash, nausea and vomiting
Prescribed For : Treatment of non-small cell lung cancer
Side Effects : Diarrhea, Dry skin, Loss of appetite, Nausea, Rash, Stomatitis (Inflammation of the mouth), Weakness, Weight loss
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 90 TABLET'S | $304.20 | $3.38 | |
| 60 TABLET'S | $203.40 | $3.39 | |
| 30 TABLET'S | $102.00 | $3.40 |
Geftinat 250 MG Tablet is a pharmaceutical medication used in the treatment of specific types of cancer. Each tablet contains gefitinib as the active ingredient, and it falls under the category of drugs known as tyrosine kinase inhibitors. Gefitinib is designed to target specific signaling pathways in the body associated with the growth and survival of cancer cells.
Here's how Geftinat works:
EGFR Inhibition:
Geftinat is classified as a tyrosine kinase inhibitor, and it primarily targets the epidermal growth factor receptor (EGFR). EGFR is a cell surface receptor involved in signaling pathways that regulate cell growth and division.
Tyrosine Kinase Inhibition:
The active ingredient in Geftinat, gefitinib, inhibits the enzymatic activity of tyrosine kinases associated with EGFR. Tyrosine kinases play a crucial role in the transmission of signals that promote cell proliferation.
Blockage of Signaling Pathways:
By inhibiting tyrosine kinases, Geftinat disrupts the downstream signaling pathways activated by EGFR. These pathways are essential for regulating various cellular processes, and their aberrant activation is a hallmark of cancer.
Cell Growth Inhibition:
The disruption of signaling pathways leads to a reduction in abnormal cell growth and division. Geftinat specifically targets cancer cells that rely on these pathways for uncontrolled proliferation.
Apoptosis Induction:
Geftinat may induce apoptosis, a programmed cell death process. This is a natural mechanism by which damaged or abnormal cells are eliminated from the body.
Targeted Therapy:
Geftinat's mechanism of action is considered targeted therapy. It focuses on inhibiting EGFR, a specific molecular target implicated in cancer growth, while sparing normal, healthy cells as much as possible.
Cancer Types:
Geftinat is particularly effective in cancers where EGFR is overexpressed or mutated. It is commonly used in the treatment of non-small cell lung cancer (NSCLC) in cases with specific genetic mutations or overexpression of EGFR.
Precision Medicine:
The targeted action of Geftinat exemplifies the concept of precision medicine, tailoring treatments to the specific molecular characteristics of the cancer. This approach aims to enhance therapeutic efficacy and minimize side effects.
Active Ingredient: Each Geftinat 250 MG Tablet contains gefitinib as the active pharmaceutical ingredient. Gefitinib is a tyrosine kinase inhibitor.
Inactive Ingredients: The inactive ingredients, also known as excipients, may vary among different formulations and brands but are not usually specified in general information.
Dosage of Geftinat 250 MG Tablets:
The dosage of Geftinat 250 MG Tablets is determined by healthcare professionals based on individual patient factors, including the type and stage of cancer. Patients are advised to take the prescribed dosage as directed by their healthcare providers.
Here are key considerations regarding who can use Geftinat 250 MG Tablets:
Non-Small Cell Lung Cancer (NSCLC):
Geftinat is commonly prescribed for the treatment of advanced or metastatic non-small cell lung cancer (NSCLC). It is particularly beneficial in cases where there are specific genetic mutations or overexpression of the epidermal growth factor receptor (EGFR).
EGFR-Positive Cancers:
The decision to use Geftinat is often based on the presence of specific molecular characteristics, such as EGFR mutations or overexpression. Individuals with EGFR-positive cancers are more likely to benefit from the targeted therapy provided by Geftinat.
Individualized Treatment Plans:
The use of Geftinat is part of an individualized treatment plan developed by healthcare professionals. Factors such as the type and stage of cancer, genetic mutations, overall health, and patient preferences are taken into account.
Under Healthcare Supervision:
Geftinat is a prescription medication, and individuals using it should be under the care and supervision of experienced healthcare professionals. Regular monitoring and assessments are typically conducted to evaluate treatment effectiveness and manage potential side effects.
Comprehensive Medical History:
Individuals should provide a comprehensive medical history to their healthcare providers, including information about existing medical conditions, current medications, and any potential allergies. This information helps healthcare professionals assess the suitability of Geftinat for each patient.
Here are some key considerations to avoid:
Missed Doses:
Missing a dose of Geftinat can affect the consistency of the medication in your system. Adhere to the prescribed schedule, and if you do miss a dose, consult your healthcare provider for guidance.
Self-Adjusting Dosage:
Do not adjust the dosage of Geftinat on your own. Changes to the prescribed dosage should only be made under the guidance of your healthcare provider.
Incorrect Timing with Meals:
Geftinat is typically taken on an empty stomach, either one hour before or two hours after meals. Adhering to these instructions ensures optimal absorption. Avoid taking it with food unless advised otherwise.
Crushing or Breaking Tablets:
Swallow Geftinat tablets whole with a full glass of water. Do not crush, break, or chew the tablets unless your healthcare provider specifically advises otherwise.
Inconsistent Timing:
Take Geftinat at the same time each day to maintain a consistent level of the medication in your body. Inconsistent timing can impact its effectiveness.
Failure to Stay Hydrated:
Diarrhea is a potential side effect of Geftinat. Ensure you stay well-hydrated unless otherwise advised by your healthcare provider. Seek medical attention if diarrhea persists.
Ignoring Side Effects:
Report any side effects to your healthcare provider promptly. Do not ignore symptoms such as skin rash, persistent diarrhea, or changes in overall well-being.
Discontinuing Treatment Without Consultation:
Do not stop taking Geftinat without consulting your healthcare provider. Abruptly discontinuing the medication can impact the effectiveness of your treatment.
Overlooking Regular Monitoring:
Regular check-ups and monitoring tests are essential during Geftinat treatment. Attend all scheduled appointments to assess treatment effectiveness and manage potential side effects.
Failure to Communicate with Healthcare Team:
Keep an open line of communication with your healthcare team. Inform them of any changes in your health, the development of new symptoms, or the use of additional medications.
Neglecting Comprehensive Medical History:
Provide your healthcare provider with a comprehensive medical history, including existing medical conditions, medications, and allergies. This information is crucial for determining the suitability of Geftinat for your specific situation.
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What is Geftinat 250 MG Tablet used for?
Geftinat is primarily used for the treatment of non-small cell lung cancer (NSCLC) with specific genetic mutations or overexpression of the epidermal growth factor receptor (EGFR).
How does Geftinat 250 MG Tablet work?
Geftinat is a tyrosine kinase inhibitor that targets the EGFR, inhibiting abnormal cell growth and division in certain cancers.
What are the common side effects of Geftinat 250 MG Tablets?
Common side effects include skin rash, diarrhea, fatigue, nausea, vomiting, loss of appetite, dry skin, eye irritation, mouth sores, changes in liver function tests, and hair changes.
How should Geftinat 250 MG Tablets be taken?
Take Geftinat orally with a full glass of water. It is usually taken on an empty stomach, either one hour before or two hours after meals. Swallow the tablet whole without crushing or chewing.
What should I do if I miss a dose of Geftinat?
If you miss a dose, take it as soon as you remember, unless it's close to the time for your next dose. Do not double up on doses. Consult your healthcare provider for guidance on missed doses.
Can I adjust the dosage of Geftinat on my own?
No, do not adjust the dosage on your own. Any changes to the prescribed dosage should be made under the guidance of your healthcare provider.
How often will I be monitored during Geftinat treatment?
Regular check-ups and monitoring tests are typically conducted to assess treatment effectiveness and manage potential side effects. Follow your healthcare provider's schedule for monitoring.
Can I stop taking Geftinat if I feel better?
No, do not stop taking Geftinat without consulting your healthcare provider. Abruptly discontinuing the medication can impact the effectiveness of your treatment.
Is it safe to use Geftinat during pregnancy or breastfeeding?
Discuss pregnancy or breastfeeding plans with your healthcare provider. Geftinat may pose risks, and a thorough evaluation of benefits and risks is essential.
What should I do if I experience severe side effects?
If you experience severe side effects or any signs of an allergic reaction, seek immediate medical attention. Report all side effects promptly to your healthcare provider.
Common side effects associated with Geftinat 250 MG Tablets may include:
Skin Rash:
Skin rash is a common side effect of Geftinat. It may manifest as redness, itching, or acne-like eruptions. Notify your healthcare provider if a rash develops.
Diarrhea:
Diarrhea is another common side effect. Maintain hydration and inform your healthcare team if diarrhea persists or becomes severe.
Fatigue:
Feeling tired or fatigued is a common occurrence. Adequate rest and proper nutrition can help manage fatigue.
Nausea and Vomiting:
Some individuals may experience nausea and vomiting. Inform your healthcare provider if these symptoms are persistent or severe.
Loss of Appetite:
A decrease in appetite may occur. Discuss any significant changes in eating habits with your healthcare team.
Infections:
Geftinat may increase the risk of infections. Report any signs of infection, such as fever or persistent cough, to your healthcare provider.
Dry Skin:
Dryness, itching, or peeling of the skin may occur. Use a mild moisturizer and inform your healthcare provider if skin issues become bothersome.
Eye Irritation:
Irritation of the eyes, including redness or dryness, can occur. Inform your healthcare team if eye symptoms persist.
Mouth Sores:
Some individuals may experience mouth sores. Maintain good oral hygiene, and notify your healthcare provider if mouth sores are a concern.
Changes in Liver Function Tests:
Geftinat can impact liver function. Regular monitoring of liver function tests is typically conducted by healthcare professionals.
Hair Changes:
Changes in hair color or texture may occur. Hair may become thinner or more brittle.
Here are the key uses of Geftinat 250 MG Tablets:
Non-Small Cell Lung Cancer (NSCLC):
Geftinat is primarily prescribed for the treatment of advanced or metastatic non-small cell lung cancer (NSCLC). It is particularly effective in cases where there are specific genetic mutations or overexpression of the epidermal growth factor receptor (EGFR).
EGFR-Positive Cancers:
The efficacy of Geftinat is often observed in cancers where there is an overexpression or mutation of the EGFR. The drug is designed to target and inhibit the activity of the EGFR tyrosine kinase, a protein involved in regulating cell growth.
Precision Medicine:
Geftinat exemplifies the concept of precision medicine in cancer treatment. It involves tailoring therapies to target specific molecular characteristics of cancer cells while minimizing the impact on normal, healthy cells.
Targeted Therapy:
As a tyrosine kinase inhibitor, Geftinat is considered targeted therapy. It specifically targets and inhibits the abnormal signaling pathways associated with cancer cell growth, providing a more focused approach compared to traditional chemotherapy.
Improved Treatment Outcomes:
Geftinat is used with the goal of improving treatment outcomes and extending the progression-free survival of individuals diagnosed with NSCLC. By targeting specific molecular abnormalities, Geftinat aims to slow down or halt the progression of the disease.
Individualized Treatment Plans:
The use of Geftinat is part of an individualized treatment plan developed by healthcare professionals based on factors such as the type and stage of cancer, genetic mutations, overall health, and patient preferences.
Here are general instructions on how to use Geftinat:
Prescription and Consultation:
Geftinat 250 MG Tablets are prescription medications. Use them only as directed by your healthcare provider. The decision to prescribe Geftinat is based on individual factors such as the type and stage of cancer.
Dosage and Schedule:
Take the tablets exactly as prescribed by your healthcare professional. The recommended dosage and administration schedule depend on individual factors, and adjustments may be made based on your response to treatment.
Oral Administration:
Geftinat is taken orally, usually with a full glass of water. Swallow the tablet whole without crushing, breaking, or chewing it. If you have difficulty swallowing, discuss alternative options with your healthcare provider.
Timing with Meals:
Geftinat is typically taken on an empty stomach, either one hour before or two hours after meals. Follow your healthcare provider's instructions regarding food restrictions around the time of administration.
Consistent Timing:
Try to take Geftinat at the same time each day to maintain a consistent level of the medication in your body. This helps optimize its effectiveness.
Missed Dose:
If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. Do not double up on doses to make up for a missed one. Consult your healthcare provider for guidance on missed doses.
Regular Monitoring:
Your healthcare provider may conduct regular check-ups and tests to monitor the effectiveness of the treatment and manage potential side effects. Attend all scheduled appointments.
Hydration:
Stay well-hydrated unless otherwise advised by your healthcare provider. Adequate hydration is important, especially if you experience diarrhea.
Adherence to Medical Advice:
Follow all additional instructions and recommendations provided by your healthcare team. Report any side effects or concerns promptly.
Comprehensive Medical History:
Inform your healthcare provider about your complete medical history, including existing medical conditions, current medications, and any allergies. This information helps healthcare professionals assess the suitability of Geftinat for each patient.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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