Generic Name : Sitagliptin + Metformin HCL
Brand Name : Istamet 50/500 mg
Manufacturer Name : Sun Pharma
Product Code : OBP 1200
Delivery Days : 10 To 12 Working Days
Composition : Sitagliptin + Metformin hcl
Strength : 50+500mg
Packaging : Tablets (Blister)
Presentation : Pills Strip
Drug Class : Dipeptidyl peptidase-4 (DPP-4) inhibitors + Biguanides
Prescribed For : Control high blood sugar levels in people with type 2 diabetes mellitus
Side Effects : Hypoglycemia, Nausea, Diarrhea, Decreased appetite, Abdominal bloating
Pack Size/Qty | Price | Price Per Pill or unit | |
90 TABLET'S | $81.00 | $0.90 | |
60 TABLET'S | $57.00 | $0.95 | |
30 TABLET'S | $30.00 | $1.00 |
Istamet 50/500 MG Tablet is a medication commonly prescribed for the management of type 2 diabetes, a chronic medical condition characterized by elevated blood sugar levels. This tablet is a combination medication that contains two active ingredients, Sitagliptin (50 mg) and Metformin (500 mg).
Istamet 50/500 MG Tablet is an effective medication for managing type 2 diabetes because it combines two distinct active ingredients, Sitagliptin and Metformin, each with its mechanism of action to regulate blood sugar levels:
Sitagliptin (50 mg): This component of Istamet is classified as a DPP-4 inhibitor. Here's how it works:
Enhances Insulin Release: Sitagliptin increases the release of insulin from the pancreas in response to rising blood sugar levels. Insulin is a hormone that helps regulate blood sugar by facilitating the uptake of glucose into cells.
Reduces Liver Glucose Production: In individuals with type 2 diabetes, the liver can sometimes produce excessive amounts of glucose, contributing to elevated blood sugar levels. Sitagliptin reduces this excess glucose production by the liver.
Metformin (500 mg): Metformin, the other active ingredient, belongs to the biguanide class of medications. It operates through several mechanisms:
Liver Glucose Reduction: Metformin lowers blood sugar levels by decreasing the liver's production of glucose. This is significant because the liver can release glucose into the bloodstream, especially when it's not needed.
Improved Insulin Sensitivity: Metformin enhances the body's sensitivity to insulin, allowing cells to take in glucose from the bloodstream more efficiently. This helps lower blood sugar levels.
Slows Glucose Absorption: Metformin also slows down the absorption of glucose from the intestines, which further contributes to better blood sugar control.
The Combined Effect: The synergy of Sitagliptin and Metformin in Istamet 50/500 MG Tablet offers comprehensive blood sugar control. While Sitagliptin helps by enhancing insulin release and reducing liver glucose production, Metformin complements this by improving insulin sensitivity and slowing down the entry of glucose into the bloodstream. This combination approach is particularly effective in managing type 2 diabetes.
Istamet 50/500 MG Tablet is a combination medication used for the management of type 2 diabetes. It contains two active ingredients, Sitagliptin (50 mg) and Metformin (500 mg). Here's a breakdown of the ingredients and dosages:
Sitagliptin (50 mg): Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It is available in a dosage of 50 milligrams per tablet. Sitagliptin works by enhancing insulin release from the pancreas in response to rising blood sugar levels. It also reduces excessive glucose production by the liver, helping to lower blood sugar levels.
Metformin (500 mg): Metformin is a biguanide medication. It is included in a dosage of 500 milligrams per tablet. Metformin operates through multiple mechanisms, including decreasing liver glucose production, improving insulin sensitivity, and slowing the absorption of glucose from the intestines. These actions collectively contribute to better blood sugar control.
Dosage Guidance:
The dosage of Istamet 50/500 MG Tablet may vary depending on an individual's specific medical condition, response to treatment, and the healthcare provider's recommendations. It's crucial to follow the prescribed dosage and administration instructions provided by your healthcare provider. The typical dosing schedule involves taking Istamet with meals to minimize the risk of stomach upset.
Istamet 50/500 MG Tablet is prescribed for individuals who have been diagnosed with type 2 diabetes, a chronic medical condition characterized by elevated blood sugar levels. Here's a breakdown of who can use Istamet:
Here are some common mistakes to avoid when using Istamet:
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Q: What is Istamet 50/500 MG Tablet used for?
A: Istamet 50/500 MG Tablet is prescribed for the management of type 2 diabetes. It helps regulate blood sugar levels in individuals with this condition.
Q: How does Istamet work?
A: Istamet combines two active ingredients, Sitagliptin and Metformin, which work together to improve insulin response, lower excessive glucose production by the liver, and enhance insulin sensitivity.
Q: What are the common side effects of Istamet 50/500 MG Tablet?
A: Common side effects may include nausea, vomiting, diarrhea, stomach discomfort, headache, and a potential risk of hypoglycemia (low blood sugar).
Q: Should Istamet be taken with or without food?
A: Istamet is typically taken with meals to reduce the risk of stomach upset. Follow your healthcare provider's instructions regarding when to take it.
Q: Can Istamet cause low blood sugar (hypoglycemia)?
A: Yes, Istamet can lower blood sugar levels, and in some cases, it may lead to hypoglycemia. Be aware of the signs of low blood sugar and take appropriate action if needed.
Q: Can Istamet be used during pregnancy?
A: The use of Istamet during pregnancy should be discussed with a healthcare provider. They will weigh the potential benefits against any risks and provide guidance.
Q: Can I drink alcohol while taking Istamet?
A: Excessive alcohol consumption can affect blood sugar levels. It's advisable to limit alcohol intake and consult your healthcare provider regarding alcohol use while on Istamet.
Q: Is it safe to drive or operate machinery while taking Istamet?
A: Istamet is generally considered safe for driving or operating machinery. However, if you experience symptoms like dizziness due to low blood sugar, avoid such activities until you are stable.
Q: Can Istamet be used in children and adolescents?
A: The use of Istamet in children and adolescents should be determined by a healthcare provider experienced in pediatric diabetes care.
Q: Is Istamet available over the counter (OTC)?
A: No, Istamet is available only with a prescription from a qualified healthcare provider.
Q: How should Istamet be stored?
A: Store Istamet as directed on the medication packaging, typically at room temperature, away from moisture and heat.
Q: Can Istamet be used as the sole treatment for diabetes?
A: Istamet is often part of a comprehensive diabetes management plan that may include dietary modifications and exercise. It is typically not used as the sole treatment.
Common side effects of Istamet may include:
Here are the primary uses of Istamet:
Here's a general guideline on how to use Istamet:
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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