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Istamet 50/500 MG Tablet is a medication commonly prescribed for the management of type 2 diabetes. It's a combination medication that incorporates two active ingredients, Sitagliptin (50 mg) and Metformin (500 mg). This combination is designed to help individuals with type 2 diabetes better control their blood sugar levels. You can buy Istamet 50/500 MG Tablets online in the USA/UK from Online Blue Pills.

ISTAMET 50/500 MG

Generic Name : Sitagliptin + Metformin HCL

Brand Name : Istamet 50/500 mg

Manufacturer Name : Sun Pharma

Product Code : OBP 1200

Delivery Days : 10 To 12 Working Days

Composition : Sitagliptin + Metformin hcl

Strength : 50+500mg

Packaging : Tablets (Blister)

Presentation : Pills Strip

Drug Class : Dipeptidyl peptidase-4 (DPP-4) inhibitors + Biguanides

Prescribed For : Control high blood sugar levels in people with type 2 diabetes mellitus

Side Effects : Hypoglycemia, Nausea, Diarrhea, Decreased appetite, Abdominal bloating

Pack Size/Qty Price Price Per Pill or unit  
90 TABLET'S $81.00 $0.90

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60 TABLET'S $57.00 $0.95

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30 TABLET'S $30.00 $1.00

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Descriptions

What is Istamet 50/500 MG Tablet?

Istamet 50/500 MG Tablet is a medication commonly prescribed for the management of type 2 diabetes, a chronic medical condition characterized by elevated blood sugar levels. This tablet is a combination medication that contains two active ingredients, Sitagliptin (50 mg) and Metformin (500 mg).


How does Istamet 50/500 MG Tablet work?

Istamet 50/500 MG Tablet is an effective medication for managing type 2 diabetes because it combines two distinct active ingredients, Sitagliptin and Metformin, each with its mechanism of action to regulate blood sugar levels:

Sitagliptin (50 mg): This component of Istamet is classified as a DPP-4 inhibitor. Here's how it works:

Enhances Insulin Release: Sitagliptin increases the release of insulin from the pancreas in response to rising blood sugar levels. Insulin is a hormone that helps regulate blood sugar by facilitating the uptake of glucose into cells.

Reduces Liver Glucose Production: In individuals with type 2 diabetes, the liver can sometimes produce excessive amounts of glucose, contributing to elevated blood sugar levels. Sitagliptin reduces this excess glucose production by the liver.

Metformin (500 mg): Metformin, the other active ingredient, belongs to the biguanide class of medications. It operates through several mechanisms:

Liver Glucose Reduction: Metformin lowers blood sugar levels by decreasing the liver's production of glucose. This is significant because the liver can release glucose into the bloodstream, especially when it's not needed.

Improved Insulin Sensitivity: Metformin enhances the body's sensitivity to insulin, allowing cells to take in glucose from the bloodstream more efficiently. This helps lower blood sugar levels.

Slows Glucose Absorption: Metformin also slows down the absorption of glucose from the intestines, which further contributes to better blood sugar control.

The Combined Effect: The synergy of Sitagliptin and Metformin in Istamet 50/500 MG Tablet offers comprehensive blood sugar control. While Sitagliptin helps by enhancing insulin release and reducing liver glucose production, Metformin complements this by improving insulin sensitivity and slowing down the entry of glucose into the bloodstream. This combination approach is particularly effective in managing type 2 diabetes.


Ingredients and dosages Istamet 50/500 MG Tablet

Istamet 50/500 MG Tablet is a combination medication used for the management of type 2 diabetes. It contains two active ingredients, Sitagliptin (50 mg) and Metformin (500 mg). Here's a breakdown of the ingredients and dosages:

Sitagliptin (50 mg): Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It is available in a dosage of 50 milligrams per tablet. Sitagliptin works by enhancing insulin release from the pancreas in response to rising blood sugar levels. It also reduces excessive glucose production by the liver, helping to lower blood sugar levels.

Metformin (500 mg): Metformin is a biguanide medication. It is included in a dosage of 500 milligrams per tablet. Metformin operates through multiple mechanisms, including decreasing liver glucose production, improving insulin sensitivity, and slowing the absorption of glucose from the intestines. These actions collectively contribute to better blood sugar control.

Dosage Guidance:

The dosage of Istamet 50/500 MG Tablet may vary depending on an individual's specific medical condition, response to treatment, and the healthcare provider's recommendations. It's crucial to follow the prescribed dosage and administration instructions provided by your healthcare provider. The typical dosing schedule involves taking Istamet with meals to minimize the risk of stomach upset.


Who can use Istamet 50/500 MG Tablet?

Istamet 50/500 MG Tablet is prescribed for individuals who have been diagnosed with type 2 diabetes, a chronic medical condition characterized by elevated blood sugar levels. Here's a breakdown of who can use Istamet:

  • Patients with Type 2 Diabetes: Istamet is primarily intended for individuals with type 2 diabetes. It is not typically used for individuals with type 1 diabetes, as their condition involves a lack of insulin production, whereas Istamet primarily works to improve insulin sensitivity and regulate blood sugar levels in type 2 diabetes.
  • Prescription Medication: Istamet 50/500 MG Tablet is available only with a prescription from a qualified healthcare provider. The decision to prescribe Istamet is made based on an individual's medical history, blood sugar levels, and overall health status.
  • Adults: It is generally prescribed for adults, and the suitability for use in adolescents and children is determined by a pediatric endocrinologist or healthcare provider experienced in pediatric diabetes care.
  • Appropriate Medical Candidates: Istamet may be considered for individuals whose blood sugar levels are not well-controlled through lifestyle modifications such as diet and exercise alone. It is also prescribed when other oral antidiabetic medications may not be sufficient in regulating blood sugar levels.
  • Individuals with a Treatment Plan: Istamet is typically included as part of a comprehensive treatment plan for type 2 diabetes. This plan may encompass medication, dietary adjustments, regular physical activity, and monitoring of blood sugar levels.
  • Individuals Who Can Follow Recommendations: Effective use of Istamet requires adherence to the prescribed dosage, timing, dietary guidelines, and lifestyle modifications recommended by the healthcare provider. Individuals who can commit to these recommendations are suitable candidates.


Common mistakes to avoid Istamet 50/500 MG Tablet

Here are some common mistakes to avoid when using Istamet:

  • Skipping Doses: Missing doses of Istamet can disrupt your blood sugar control. Avoid skipping doses, and if you accidentally miss one, take it as soon as you remember, unless it's close to the time for your next scheduled dose.
  • Not Taking with Meals: Istamet is typically taken with meals to reduce the risk of stomach upset. Avoid taking it on an empty stomach unless your healthcare provider advises otherwise.
  • Changing Dosage Without Consultation: Do not alter the dosage or frequency of Istamet without consulting your healthcare provider. Changes should be made only under their guidance.
  • Ignoring Dietary Recommendations: Istamet is often part of a comprehensive diabetes management plan that includes dietary modifications. Ignoring dietary guidelines can lead to poor blood sugar control. Follow your healthcare provider's dietary recommendations.
  • Neglecting Regular Exercise: Regular physical activity is essential in managing type 2 diabetes. Avoid a sedentary lifestyle and include exercise as recommended by your healthcare provider.
  • Not Monitoring Blood Sugar: Regularly monitor your blood sugar levels as advised by your healthcare provider. Neglecting this can make it challenging to assess the effectiveness of Istamet and adjust your treatment plan if needed.
  • Ignoring Side Effects: If you experience any side effects while using Istamet, do not ignore them. Common side effects may include nausea, diarrhea, or stomach upset. Consult your healthcare provider about any unusual or severe symptoms.
  • Alcohol Abuse: Excessive alcohol consumption can affect blood sugar levels and interact with Istamet. Limit alcohol intake and discuss alcohol use with your healthcare provider.
  • Not Communicating with Your Healthcare Provider: Effective diabetes management requires open communication with your healthcare provider. Share any concerns, questions, or changes in your health with them.
  • Discontinuing Medication: Do not discontinue Istamet abruptly or without your healthcare provider's guidance, even if your blood sugar levels improve. Diabetes is a chronic condition that requires ongoing management.
  • Overlooking Medication Interactions: Inform your healthcare provider of all medications, supplements, or herbal remedies you are taking. Some medications can interact with Istamet, affecting its effectiveness or causing side effects.
  • Self-Diagnosis and Treatment: Do not attempt to self-diagnose or self-treat diabetes. Always seek a proper diagnosis and treatment plan from a qualified healthcare provider.
  • Failure to Attend Check-ups: Regular check-ups with your healthcare provider are essential to monitor your diabetes management and make necessary adjustments to your treatment plan. Avoid skipping these appointments.


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Faq

FAQs on Istamet 50/500 MG Tablet


Q: What is Istamet 50/500 MG Tablet used for?


A: Istamet 50/500 MG Tablet is prescribed for the management of type 2 diabetes. It helps regulate blood sugar levels in individuals with this condition.


Q: How does Istamet work?


A: Istamet combines two active ingredients, Sitagliptin and Metformin, which work together to improve insulin response, lower excessive glucose production by the liver, and enhance insulin sensitivity.


Q: What are the common side effects of Istamet 50/500 MG Tablet?


A: Common side effects may include nausea, vomiting, diarrhea, stomach discomfort, headache, and a potential risk of hypoglycemia (low blood sugar).


Q: Should Istamet be taken with or without food?


A: Istamet is typically taken with meals to reduce the risk of stomach upset. Follow your healthcare provider's instructions regarding when to take it.


Q: Can Istamet cause low blood sugar (hypoglycemia)?


A: Yes, Istamet can lower blood sugar levels, and in some cases, it may lead to hypoglycemia. Be aware of the signs of low blood sugar and take appropriate action if needed.


Q: Can Istamet be used during pregnancy?


A: The use of Istamet during pregnancy should be discussed with a healthcare provider. They will weigh the potential benefits against any risks and provide guidance.


Q: Can I drink alcohol while taking Istamet?


A: Excessive alcohol consumption can affect blood sugar levels. It's advisable to limit alcohol intake and consult your healthcare provider regarding alcohol use while on Istamet.


Q: Is it safe to drive or operate machinery while taking Istamet?


A: Istamet is generally considered safe for driving or operating machinery. However, if you experience symptoms like dizziness due to low blood sugar, avoid such activities until you are stable.


Q: Can Istamet be used in children and adolescents?


A: The use of Istamet in children and adolescents should be determined by a healthcare provider experienced in pediatric diabetes care.


Q: Is Istamet available over the counter (OTC)?


A: No, Istamet is available only with a prescription from a qualified healthcare provider.


Q: How should Istamet be stored?


A: Store Istamet as directed on the medication packaging, typically at room temperature, away from moisture and heat.


Q: Can Istamet be used as the sole treatment for diabetes?


A: Istamet is often part of a comprehensive diabetes management plan that may include dietary modifications and exercise. It is typically not used as the sole treatment.

Side Effect

Common side effects of Istamet 50/500 MG Tablet

Common side effects of Istamet may include:

  • Nausea: Some individuals may experience mild to moderate nausea, particularly when they start taking Istamet. This effect can often be managed by taking the medication with food.
  • Vomiting: Vomiting may occur in some cases, especially when Istamet is taken without food. Taking it with meals can help reduce the likelihood of vomiting.
  • Diarrhea: Diarrhea can be a common side effect of Istamet. It's important to stay well-hydrated if diarrhea occurs, and consult your healthcare provider if it persists.
  • Stomach Upset or Discomfort: Some individuals may experience general stomach discomfort or bloating while using Istamet.
  • Headache: Mild headaches are occasionally reported as a side effect of Istamet.
  • Hypoglycemia (Low Blood Sugar): While not common, Istamet can cause low blood sugar levels, especially if the dosage is too high or if it's taken with other medications that lower blood sugar. Symptoms of hypoglycemia may include sweating, shakiness, rapid heartbeat, confusion, and dizziness. It's important to be aware of the signs of low blood sugar and take appropriate action to raise blood sugar levels if needed.
  • Upper Respiratory Tract Infection: Some individuals using Istamet may experience upper respiratory tract infections, such as a common cold or sore throat.
  • Increased Risk of Infection: Istamet can lower the body's ability to fight infections. If you develop any signs of infection, such as fever, chills, or persistent sore throat, consult your healthcare provider.
  • Elevated Liver Enzymes: In rare cases, Istamet may cause a temporary increase in liver enzyme levels. Your healthcare provider will monitor your liver function during treatment.

Uses

Uses of Istamet 50/500 MG Tablet

Here are the primary uses of Istamet:

  • Blood Sugar Regulation: The primary purpose of Istamet is to regulate and control blood sugar levels in individuals with type 2 diabetes. It achieves this by improving the body's response to insulin and reducing excessive glucose production by the liver.
  • Enhanced Insulin Sensitivity: Istamet includes Metformin, which enhances the body's sensitivity to insulin. This means that cells are better able to absorb and utilize glucose from the bloodstream, helping to lower blood sugar levels.
  • Lowering Liver Glucose Production: Metformin, one of the active ingredients in Istamet, reduces the liver's production of glucose. In individuals with type 2 diabetes, the liver can sometimes release too much glucose into the bloodstream, contributing to elevated blood sugar levels. Istamet helps control this excess production.
  • Improved Blood Sugar Control: By combining two distinct medications, Sitagliptin and Metformin, Istamet offers a comprehensive approach to blood sugar control. Sitagliptin enhances insulin release and reduces liver glucose production, while Metformin improves insulin sensitivity and slows glucose absorption from the intestines.
  • Prevention of Complications: Effective management of blood sugar levels with Istamet can help reduce the risk of complications associated with uncontrolled type 2 diabetes. These complications may include cardiovascular disease, kidney problems, nerve damage, and eye issues.
  • Part of a Comprehensive Treatment Plan: Istamet is typically prescribed as part of a broader diabetes management plan, which may also include dietary modifications, regular physical activity, and consistent monitoring of blood sugar levels. This holistic approach aims to achieve optimal blood sugar control and overall health.


How to use Istamet 50/500 MG Tablet?

Here's a general guideline on how to use Istamet:

  • Prescription Only: Istamet is available only with a prescription from a qualified healthcare provider. Ensure that you have a valid prescription before using this medication.
  • Dosage: Istamet is available in various dosages, and your healthcare provider will determine the appropriate dosage based on your individual medical history, blood sugar levels, and response to treatment. Always follow the dosage instructions provided by your healthcare provider.
  • Timing: Istamet is usually taken with meals to minimize the risk of stomach upset. Your healthcare provider will specify the timing of your doses. It's essential to adhere to this schedule consistently.
  • Swallow Whole: Take Istamet tablets whole with a glass of water. Do not crush, break, or chew the tablets unless your healthcare provider advises otherwise.
  • Regular Use: Istamet is typically taken daily as part of a long-term diabetes management plan. It should be used consistently, even if you feel well, to maintain stable blood sugar levels.
  • Follow Healthcare Provider's Guidance: It's crucial to closely follow your healthcare provider's recommendations regarding Istamet's usage, including the dosage, timing, and any dietary or lifestyle modifications.
  • Monitor Blood Sugar: Regularly monitor your blood sugar levels as advised by your healthcare provider. This will help assess the medication's effectiveness and enable adjustments to your treatment plan if necessary.
  • Diet and Exercise: Continue to follow any dietary and exercise recommendations provided by your healthcare provider. Lifestyle modifications are an essential part of managing type 2 diabetes.
  • Missed Dose: If you miss a dose of Istamet, take it as soon as you remember, unless it's close to the time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
  • Storage: Store Istamet tablets as directed on the medication packaging. Typically, they should be kept at room temperature, away from moisture and heat.
  • Side Effects: Be aware of potential side effects, and if you experience any unusual or severe symptoms while using Istamet, consult your healthcare provider.
  • Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor your diabetes management and make any necessary adjustments to your treatment plan.

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Disclaimer

The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.

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