Generic Name : Eloxatin
Brand Name : Oxiplatin
Manufacturer Name : Fresenius Kabi
Product Code : OBP 937
Delivery Days : 10 To 12 Working Days
Composition : Eloxatin
Strength : 50mg
Packaging : Injection Vial Bottle
Presentation : Injection Vial
Drug Class : Antineoplastic agents
Prescribed For : Treatment of cancer of colon and rectum
Side Effects : Nausea, vomiting, mouth ulcers, loss of appetite, indigestion, numbness, nerve pain
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 05 INJECTION'S | $157.20 | $31.44 | |
| 03 INJECTION'S | $85.77 | $28.59 | |
| 01 INJECTION'S | $55.74 | $55.74 |
Oxitan 50MG/25ML is a chemotherapy medication used in the treatment of specific types of cancer. The active ingredient in Oxitan is oxaliplatin, a platinum-based compound known for its cytotoxic effects on rapidly dividing cancer cells. This medication is administered intravenously, typically in a hospital or outpatient setting, and is an integral part of cancer treatment protocols.
Here's how Oxitan works:
Platinum Complex Formation:
Oxaliplatin, the active component of Oxitan, forms a platinum-containing complex. This complex is critical for the drug's activity against cancer cells.
DNA Binding:
Once administered intravenously, Oxitan enters the bloodstream and reaches the cancer cells. Within the cells, the platinum complex binds to the DNA strands.
DNA Cross-Linking:
The binding of the platinum complex to DNA induces the formation of cross-links within the DNA structure. These cross-links interfere with the normal functioning of DNA, specifically hindering the replication and transcription processes.
DNA Damage:
The cross-linking of DNA prevents the accurate separation of DNA strands during cell division. As a result, the cancer cells are unable to replicate properly, leading to DNA damage.
Cell Cycle Arrest:
The DNA damage caused by Oxitan activates cellular mechanisms that arrest the cell cycle. This arrest prevents cancer cells from progressing through the cell cycle and dividing.
Induction of Apoptosis:
The disruption of DNA integrity and the cell cycle arrest trigger programmed cell death, known as apoptosis, in the cancer cells. Apoptosis is a natural process that eliminates damaged or abnormal cells from the body.
Cytotoxic Effect:
The cumulative effect of DNA damage, cell cycle arrest, and apoptosis results in the cytotoxicity of Oxitan. Cancer cells are selectively targeted and eliminated due to their increased susceptibility to DNA alterations.
Synergy in Combination Therapies:
Oxitan is often used in combination with other chemotherapy agents. The combination therapy aims to enhance the overall effectiveness of treatment by targeting cancer cells through multiple mechanisms, reducing the risk of resistance.
Active Ingredient:
The active ingredient in Oxitan 50MG/25ML is oxaliplatin. Oxaliplatin is a platinum-containing compound with cytotoxic properties used in chemotherapy for the treatment of certain types of cancer.
Dosage Information:
The dosage of Oxitan 50MG/25ML is determined by the treating oncologist based on various factors, including the type and stage of cancer, the patient's overall health, and individualized treatment plans.
Administration:
Oxitan 50MG/25ML is administered intravenously (IV). The intravenous infusion is typically performed by healthcare professionals in a clinical setting, such as a hospital or outpatient infusion center.
Here's a general overview:
Colorectal Cancer Patients:
Oxitan is commonly used in the treatment of colorectal cancer. Patients diagnosed with colorectal cancer may be considered for Oxitan as part of their cancer treatment plan.
Staging and Type of Cancer:
The decision to use Oxitan depends on the staging and specific characteristics of the cancer. It may be employed in both adjuvant therapy after surgery to prevent cancer recurrence and in metastatic settings for advanced cases.
Individualized Treatment Plans:
Oxitan is often part of individualized treatment plans designed by oncologists. The choice to include Oxitan is based on factors such as the patient's overall health, the stage of cancer, and the goals of treatment.
Combination Therapy Recipients:
Oxitan is frequently used in combination with other chemotherapy agents to create a comprehensive and synergistic treatment approach. This combination therapy is aimed at maximizing the effectiveness of cancer treatment.
Medical Evaluation:
Prior to initiating Oxitan treatment, individuals undergo a thorough medical evaluation. This includes assessments of overall health, blood counts, kidney function, and other relevant parameters.
Monitoring and Follow-Up:
Patients receiving Oxitan are closely monitored throughout the course of treatment. Regular follow-up appointments with the oncologist are scheduled to assess treatment response, manage side effects, and make any necessary adjustments to the treatment plan.
Pregnancy Considerations:
Oxitan may cause harm to a developing fetus, so pregnant individuals or those planning to become pregnant should discuss the risks and benefits with their healthcare team before starting treatment.
Here are common mistakes to avoid:
Incorrect Dosage or Administration:
Mistakes in calculating or administering the dosage of Oxitan can have serious consequences. Healthcare professionals must accurately determine the appropriate dosage based on the patient's weight, overall health, and treatment plan.
Inadequate Monitoring During Infusion:
Failure to closely monitor patients during the intravenous infusion of Oxitan may lead to a delayed response to potential side effects or adverse reactions. Regular monitoring is crucial for patient safety.
Missed or Delayed Follow-Up Appointments:
Regular follow-up appointments with the oncologist are essential to assess treatment response and manage side effects. Missing or delaying these appointments can compromise the effectiveness of the treatment plan.
Failure to Communicate Side Effects:
Patients should promptly communicate any side effects or concerns to their healthcare team. Failure to report side effects in a timely manner may result in inadequate management of symptoms.
Neglecting Pre-Medications:
Pre-medications prescribed to prevent or minimize side effects, such as nausea, should not be neglected. Skipping these pre-medications may lead to increased discomfort during and after the treatment.
Inconsistent Adherence to Treatment Plan:
Adherence to the prescribed treatment plan, including dosage schedules and rest periods, is crucial for the success of chemotherapy. Inconsistent adherence may compromise the efficacy of the treatment.
Lack of Pregnancy Precautions:
Oxitan may cause harm to a developing fetus. It's essential for both healthcare providers and patients to take appropriate precautions and discuss family planning considerations before starting treatment, especially in women of childbearing age.
Failure to Address Neuropathy Symptoms:
Oxitan is known to cause peripheral neuropathy. Patients should not neglect symptoms such as tingling or numbness in the hands and feet, as early intervention can help manage neuropathy and prevent its progression.
Not Discussing Treatment Goals and Concerns:
Patients should actively engage in discussions with their healthcare team about treatment goals, potential side effects, and any concerns they may have. Open communication fosters a collaborative approach to care.
Not Seeking Second Opinions:
In complex cases or when faced with challenging treatment decisions, seeking a second opinion from another oncologist can provide valuable insights and enhance the overall decision-making process.
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What is Oxitan 50MG/25ML used for?
Oxitan 50MG/25ML is a chemotherapy medication primarily used in the treatment of certain types of cancer, with a focus on colorectal cancer. It may be employed in adjuvant therapy after surgery or in the management of metastatic colorectal cancer.
How is Oxitan 50MG/25ML administered?
Oxitan 50MG/25ML is administered intravenously (IV) by healthcare professionals. The intravenous infusion is typically performed in a clinical setting, such as a hospital or outpatient infusion center.
What are the common side effects of Oxitan 50MG/25ML?
Common side effects include peripheral neuropathy (tingling or numbness in hands and feet), nausea, vomiting, fatigue, diarrhea, hypersensitivity reactions, hematological changes, cold sensitivity, muscle and joint pain, changes in taste, and hair loss.
How is peripheral neuropathy managed during Oxitan treatment?
Peripheral neuropathy is a common side effect, and its management may involve dose adjustments, medications for symptom relief, and proactive measures to protect extremities from cold temperatures.
Are there medications to prevent nausea and vomiting with Oxitan?
Yes, anti-nausea medications may be prescribed to manage nausea and vomiting associated with Oxitan treatment. Patients should take these medications as directed by their healthcare team.
Can Oxitan cause allergic reactions?
While rare, Oxitan can cause hypersensitivity reactions. Symptoms may include rash, itching, swelling, or difficulty breathing. Immediate medical attention is necessary if such reactions occur.
How often is Oxitan 50MG/25ML administered?
The frequency of Oxitan administration and the number of treatment cycles depend on the individualized treatment plan designed by the oncologist. The treatment may involve several cycles, with each cycle followed by a rest period.
Is hair loss a common side effect of Oxitan?
Yes, hair loss (alopecia) is a potential side effect of Oxitan treatment. However, hair typically begins to grow back after the completion of chemotherapy.
Can Oxitan be used during pregnancy?
Oxitan may cause harm to a developing fetus. Pregnant individuals or those planning to become pregnant should discuss family planning considerations with their healthcare team before starting treatment.
Is it advisable to seek a second opinion before starting Oxitan treatment?
In complex cases or when faced with challenging treatment decisions, seeking a second opinion from another oncologist is a common and advisable practice. It can provide additional insights and enhance the overall decision-making process.
Common side effects of Oxitan include:
Peripheral Neuropathy:
Tingling, numbness, or pain in the hands and feet, known as peripheral neuropathy, is a common side effect of Oxitan. It may affect daily activities and require dose adjustments.
Nausea and Vomiting:
Gastrointestinal symptoms, including nausea and vomiting, are commonly associated with Oxitan. Anti-nausea medications may be prescribed to manage these effects.
Fatigue:
Feeling tired or fatigued is a common side effect. Patients are encouraged to get adequate rest and communicate with their healthcare team if fatigue becomes severe.
Diarrhea:
Diarrhea is a gastrointestinal side effect that may occur. Hydration and medications to control diarrhea may be recommended.
Hypersensitivity Reactions:
Allergic reactions, though rare, can occur. Symptoms may include rash, itching, swelling, or difficulty breathing. Immediate medical attention is necessary if such reactions occur.
Hematological Changes:
Oxitan can affect blood cell counts, leading to changes such as anemia (low red blood cell count), thrombocytopenia (low platelet count), and leukopenia (low white blood cell count). Regular blood tests are conducted to monitor these parameters.
Cold Sensitivity:
Increased sensitivity to cold, particularly in the hands and throat, is a characteristic side effect. Patients may experience discomfort when exposed to cold temperatures.
Muscle and Joint Pain:
Muscular and joint pain, often described as achiness, is reported by some individuals undergoing Oxitan treatment. This pain can be managed with appropriate medications.
Changes in Taste:
Altered taste sensation, including a metallic taste in the mouth, is a common side effect. This can affect appetite and food preferences.
Hair Loss:
Some patients may experience hair loss (alopecia) as a side effect of Oxitan treatment. Hair typically grows back after the completion of chemotherapy.
Here are the key uses of Oxitan:
Colorectal Cancer:
The primary and prominent use of Oxitan is in the treatment of colorectal cancer. It is indicated for both adjuvant therapy, following surgery to prevent cancer recurrence, and in metastatic settings for advanced cases where the cancer has spread.
Adjuvant Therapy:
Oxitan may be prescribed as part of adjuvant therapy, which is treatment given after the primary treatment (usually surgery) to eliminate any remaining cancer cells and reduce the risk of cancer recurrence.
Metastatic Colorectal Cancer:
In cases where colorectal cancer has metastasized, meaning it has spread to other parts of the body, Oxitan is often included as a component of the chemotherapy regimen.
Combination Therapy:
Oxitan is frequently used in combination with other chemotherapy agents. Combination therapy is designed to enhance the overall effectiveness of cancer treatment by targeting cancer cells through multiple mechanisms, reducing the risk of resistance.
Synergistic Treatment Approach:
The drug is part of a synergistic treatment approach, where it works in tandem with other medications to create a comprehensive and potent strategy against cancer cells.
Interrupting Cancer Cell Growth:
Oxitan, containing oxaliplatin, functions by interfering with the DNA in rapidly dividing cancer cells. This interference disrupts the cancer cells' ability to replicate and divide, ultimately leading to cell death.
Individualized Treatment Plans:
The use of Oxitan is determined based on individual patient factors, including the type and stage of cancer, overall health, and treatment goals. Oncologists develop personalized treatment plans to optimize therapeutic outcomes.
Here is a general overview of how Oxitan is typically used:
Administration by Healthcare Professionals:
Oxitan 50MG/25ML is administered intravenously (IV) by healthcare professionals. The intravenous infusion is typically performed in a clinical setting, such as a hospital or outpatient infusion center.
Dosage and Treatment Cycles:
The dosage of Oxitan and the treatment schedule are determined by the treating oncologist based on factors such as the type and stage of cancer, overall health, and treatment goals. The medication is often organized into cycles, with each cycle followed by a rest period.
Individualized Treatment Plans:
Treatment plans with Oxitan are individualized for each patient. The oncologist carefully considers the patient's specific medical condition and response to treatment when designing the plan.
Combination Therapy:
Oxitan is often used in combination with other chemotherapy agents. The combination therapy is designed to maximize the effectiveness of cancer treatment by targeting cancer cells through different mechanisms.
Monitoring During Infusion:
Throughout the infusion process, patients are closely monitored for any signs of adverse reactions or side effects. Healthcare professionals will ensure that the infusion proceeds smoothly and safely.
Prevention of Side Effects:
Patients may receive pre-medications to help prevent or minimize potential side effects such as nausea or allergic reactions. These pre-medications are prescribed based on the individual patient's needs.
Follow-Up Appointments:
Regular follow-up appointments with the oncologist are scheduled to assess treatment response, manage side effects, and make any necessary adjustments to the treatment plan. Patients are encouraged to communicate openly about their experiences during and after treatment.
Adherence to Treatment Plan:
It is crucial for patients to adhere to the prescribed dosage and administration schedule. Any concerns or questions about the treatment should be discussed with the healthcare team.
Pregnancy Considerations:
Due to the potential harm to a developing fetus, pregnant individuals or those planning to become pregnant should discuss the risks and benefits with their healthcare team before starting treatment.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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