Generic Name : Azacitidine
Brand Name : Vidaza
Manufacturer Name : Intas Pharma
Product Code : OBP 1057
Delivery Days : 10 To 12 Working Days
Composition : Azacitidine
Strength : 100mg
Packaging : Injection Vial Bottle
Presentation : Injection Vial
Drug Class : Demethylation agents
Prescribed For : Treatment of some kinds of blood cancer
Side Effects : Injection site reactions (pain, swelling, redness), Vomiting, Weakness, Nausea, Decreased potassium level in blood, Bruise, Fever, Chills
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 09 VIAL'S | $1,556.91 | $172.99 | |
| 06 VIAL'S | $1,043.94 | $173.99 | |
| 03 VIAL'S | $530.97 | $176.99 | |
| 01 VIAL | $181.99 | $181.99 |
Azadine 100 MG Injection is a pharmaceutical product containing azacitidine as its active ingredient. It falls under the category of demethylation agents, a class of medications used in the treatment of certain blood cancers.
Azadine 100 MG Injection exerts its therapeutic effects through a mechanism that involves interference with DNA methylation, a crucial process in gene regulation. Here's how Azadine works:
DNA Methylation:
DNA methylation is an epigenetic modification that involves the addition of a methyl group to the DNA molecule. This modification plays a key role in regulating gene expression, determining which genes are turned on or off in a cell.
Abnormal DNA Methylation in Cancer:
In certain types of cancer, including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), there can be abnormal DNA methylation patterns. These aberrations contribute to the uncontrolled growth and division of cancer cells.
Azadine as a Demethylating Agent:
Azadine contains azacitidine, which acts as a demethylating agent. Azacitidine is a nucleoside analogue that gets incorporated into the DNA during cell division.
Incorporation into DNA:
When cells replicate their DNA, azacitidine is incorporated into the newly forming DNA strands in place of cytidine. This incorporation disrupts the normal DNA methylation patterns.
Inhibition of DNA Methyltransferase:
Azacitidine inhibits the activity of DNA methyltransferase, an enzyme responsible for adding methyl groups to DNA. By inhibiting this enzyme, azacitidine contributes to the reduction of abnormal DNA methylation in cancer cells.
Changes in Gene Expression:
The alteration in DNA methylation patterns leads to changes in gene expression. Some genes that were previously silenced may become active, while the expression of other genes involved in uncontrolled cell growth may be suppressed.
Cellular Effects:
The overall effect of Azadine's demethylating action is to promote a more normal pattern of gene expression in cancer cells. This, in turn, can contribute to the inhibition of abnormal cell growth and induction of programmed cell death (apoptosis).
Treatment of Blood Cancers:
In the context of blood cancers like MDS and AML, the demethylating action of Azadine helps target and regulate the growth of abnormal blood cells.
Ingredients and dosages Azadine 100 MG Injection
The active pharmaceutical ingredient in Azadine 100 MG Injection is azacitidine. Each injection contains a specific quantity of azacitidine, measured in milligrams.
Dosage of Azadine 100 MG Injection:
The dosage of Azadine 100 MG Injection is determined by healthcare professionals based on several factors, including the specific type of blood cancer being treated, the patient's overall health, and individual response to the medication.
The injection is administered intravenously (IV) by healthcare providers. The recommended dosage and infusion schedule are part of an individualized treatment plan developed for each patient.
Dosages are expressed in milligrams (MG), and the frequency of administration may vary. Patients are advised to adhere to the prescribed dosage and infusion schedule provided by their healthcare team.
Azadine 100 MG Injection is prescribed for individuals diagnosed with specific types of blood cancer, particularly myelodysplastic syndromes (MDS) and, in certain cases, acute myeloid leukemia (AML). The decision to use Azadine is typically made by healthcare professionals based on several factors:
Type of Blood Cancer:
Azadine is commonly used in the treatment of myelodysplastic syndromes (MDS), a group of disorders characterized by dysfunctional blood cell production in the bone marrow.
Specific Subtypes of MDS:
The use of Azadine may be tailored to specific subtypes of myelodysplastic syndromes. The decision is influenced by the individual characteristics of the patient's disease.
Acute Myeloid Leukemia (AML):
In some situations, Azadine may also be considered in the treatment of acute myeloid leukemia (AML), a type of cancer affecting the blood and bone marrow.
Individualized Treatment Plans:
The use of Azadine is part of an individualized treatment plan developed by healthcare professionals based on factors such as the type and stage of blood cancer, the patient's overall health, genetic considerations, and specific laboratory results.
Self-Administration:
Mistake: Attempting to self-administer Azadine 100 MG Injection without proper training or supervision.
Prevention: Always have healthcare professionals administer the injection in a clinical setting.
Missed Appointments:
Mistake: Missing scheduled appointments for Azadine administration and monitoring.
Prevention: Adhere to the recommended schedule and attend all follow-up appointments as directed by your healthcare provider.
Dosage Adjustments Without Consultation:
Mistake: Adjusting the dosage of Azadine without consulting your healthcare provider.
Prevention: Any changes to the dosage should be discussed with and approved by your healthcare team.
Discontinuation Without Consultation:
Mistake: Abruptly stopping Azadine treatment without consulting your healthcare provider.
Prevention: Always communicate with your healthcare team before considering any changes to your treatment plan.
Incomplete Understanding:
Mistake: Failing to fully understand the purpose, potential side effects, and expected outcomes of Azadine treatment.
Prevention: Seek clarification from your healthcare provider if any aspects of the treatment plan are unclear.
Failure to Report Side Effects:
Mistake: Neglecting to report side effects or health changes promptly to your healthcare provider.
Prevention: Communicate openly with your healthcare team, reporting any new or worsening symptoms.
Inconsistent Follow-Up Monitoring:
Mistake: Inconsistent participation in recommended follow-up monitoring appointments.
Prevention: Attend all scheduled monitoring appointments to assess treatment response and manage potential side effects.
Storage Negligence:
Mistake: Improper storage of Azadine 100 MG Injection.
Prevention: Follow the storage guidelines provided by your healthcare provider or pharmacist to maintain the integrity of the medication.
Combining with Unapproved Medications:
Mistake: Taking additional medications or supplements without consulting your healthcare provider.
Prevention: Inform your healthcare team about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.
Delay in Reporting Health Changes:
Mistake: Delaying reporting of significant health changes or the development of new symptoms.
Prevention: Act promptly by informing your healthcare provider of any notable changes in your health.
Failure to Discuss Pregnancy or Breastfeeding Plans:
Mistake: Neglecting to discuss pregnancy or breastfeeding plans with your healthcare provider.
Prevention: Consult your healthcare team to assess the potential risks and benefits of Azadine in relation to pregnancy or breastfeeding.
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What is Azadine 100 MG Injection used for?
Azadine 100 MG Injection is used in the treatment of specific types of blood cancer, including myelodysplastic syndromes (MDS) and, in certain cases, acute myeloid leukemia (AML). It functions as a demethylating agent to inhibit abnormal cell growth.
How is Azadine 100 MG Injection administered?
Azadine is administered by healthcare professionals through intravenous (IV) infusion. The dosage and infusion schedule are determined based on the specific type of blood cancer and individual patient factors.
What are the common side effects of Azadine 100 MG Injection?
Common side effects may include nausea, vomiting, fatigue, fever, anemia, injection site reactions, bruising, constipation, diarrhea, headache, dizziness, muscle or joint pain, rash, changes in liver enzymes, decreased appetite, swelling, cough, shortness of breath, infection, and abdominal pain.
Are there any serious side effects of Azadine 100 MG Injection?
Serious side effects can occur. Patients should promptly report any unusual or severe symptoms to their healthcare provider. Serious side effects may include severe infections, bleeding, and changes in liver function.
Can Azadine 100 MG Injection be self-administered?
No, Azadine should be administered by healthcare professionals in a clinical setting. Attempting self-administration without proper training or supervision is not recommended.
Is it safe to become pregnant or breastfeed while using Azadine 100 MG Injection?
Patients should discuss pregnancy or breastfeeding plans with their healthcare provider. Azadine may have potential risks, and a healthcare professional can provide guidance based on individual circumstances.
Can Azadine 100 MG Injection be combined with other medications?
Patients should inform their healthcare team about all medications, including over-the-counter drugs and supplements, to avoid potential interactions. Changes to medication regimens should be discussed with healthcare providers.
How often are monitoring appointments required during Azadine treatment?
Regular monitoring appointments are essential to assess treatment response and manage potential side effects. The frequency of appointments is determined by the healthcare provider and may vary based on individual circumstances.
What should I do if I miss a scheduled Azadine 100 MG Injection appointment?
Patients should contact their healthcare provider promptly if they miss a scheduled appointment. It is important to follow up with healthcare professionals to ensure continuity of care.
How should Azadine 100 MG Injection be stored?
Patients should follow the storage guidelines provided by their healthcare provider or pharmacist to maintain the integrity of the medication. Proper storage contributes to the effectiveness and safety of Azadine.
Nausea:
Feeling of discomfort or queasiness in the stomach.
Vomiting:
The act of expelling stomach contents through the mouth.
Fatigue:
Persistent feeling of tiredness or lack of energy.
Fever:
Elevated body temperature beyond the normal range.
Anemia:
Reduction in red blood cell count, leading to fatigue, weakness, and pallor.
Injection Site Reactions:
Redness, swelling, or pain at the site where the injection is administered.
Bruising:
Development of purple or red discoloration under the skin due to bleeding.
Constipation:
Difficulty in passing stools or infrequent bowel movements.
Diarrhea:
Increased frequency of loose or watery stools.
Headache:
Pain or discomfort in the head.
Dizziness:
Feeling lightheaded or unsteady.
Muscle or Joint Pain:
Discomfort or pain in the muscles or joints.
Rash:
Abnormal changes in the skin, such as redness or itching.
Changes in Liver Enzymes:
Alterations in liver function tests may occur.
Decreased Appetite:
Reduced desire or interest in eating.
Swelling (Edema):
Accumulation of fluid leading to swelling, often in the ankles or legs.
Cough:
Sudden, forceful expulsion of air from the lungs.
Shortness of Breath:
Difficulty in breathing or a feeling of breathlessness.
Infection:
Increased susceptibility to infections due to changes in the immune system.
Abdominal Pain:
Discomfort or cramping in the abdominal area.
Azadine 100 MG Injection is prescribed for the treatment of specific types of blood cancer. The primary indications include:
Myelodysplastic Syndromes (MDS):
Azadine is commonly used in the treatment of myelodysplastic syndromes, a group of disorders characterized by abnormal blood cell production in the bone marrow. MDS is often associated with genetic mutations and can progress to acute myeloid leukemia.
Acute Myeloid Leukemia (AML):
In certain cases, Azadine may be considered in the treatment of acute myeloid leukemia. AML is a type of cancer that affects the blood and bone marrow, leading to the rapid growth of abnormal white blood cells.
Administration by Healthcare Professionals:
Azadine 100 MG Injection is administered by healthcare professionals, typically in a clinical setting. It is given through intravenous (IV) infusion.
Individualized Dosage and Schedule:
The dosage and infusion schedule of Azadine are determined by healthcare providers based on various factors, including the specific type and stage of blood cancer, the patient's overall health, and individual response to the medication.
Intravenous (IV) Infusion:
The injection is administered directly into a vein through an intravenous line. The infusion is done over a specific period of time, and the rate of administration is carefully controlled.
Dosage in Milligrams (MG):
The dosage is expressed in milligrams (MG), and patients should adhere to the prescribed amount specified by their healthcare provider.
Frequency of Administration:
The frequency of Azadine administration may vary depending on the individual treatment plan. It is essential for patients to follow the recommended schedule provided by their healthcare team.
Regular Monitoring:
Patients receiving Azadine 100 MG Injection are typically monitored regularly to assess treatment effectiveness and manage potential side effects. This monitoring includes laboratory tests to evaluate blood counts and other relevant parameters.
Adherence to Instructions:
Patients should strictly adhere to the instructions provided by their healthcare provider regarding the administration of Azadine. Any questions or concerns about the treatment should be addressed promptly.
Follow-up Appointments:
Attend all scheduled follow-up appointments with your healthcare provider. These appointments are crucial for evaluating the response to treatment, making any necessary adjustments to the treatment plan, and addressing any concerns or side effects.
Communication with Healthcare Team:
Open communication with the healthcare team is essential. Patients should report any side effects, changes in health, or other concerns promptly to ensure a comprehensive and well-monitored treatment experience.
Storage and Handling:
Azadine 100 MG Injection should be stored and handled as per the instructions provided by the healthcare provider or pharmacist. Follow any specific storage guidelines to maintain the integrity of the medication.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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