Generic Name : Glimepiride
Brand Name : Amaryl
Manufacturer Name : Sun Pharma
Product Code : OBP 318
Delivery Days : 10 To 12 Working Days
Composition : Glimepiride
Strength : 2mg
Packaging : Tablet (Blisters)
Presentation : Pills Strip
Drug Class : Dipeptidyl peptidase-4 (DPP-4) inhibitors
Prescribed For : Treat type 2 diabetes mellitus
Side Effects : Low blood sugar levels (hypoglycemia), nausea, headache, and dizziness
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 90 TABLET'S | $26.10 | $0.29 | |
| 60 TABLET'S | $19.80 | $0.33 | |
| 30 TABLET'S | $12.30 | $0.41 |
Glypride 2 MG Tablets are a medication prescribed for the management of type 2 diabetes mellitus. Each tablet contains the active ingredient glimepiride, a sulfonylurea derivative that aids in controlling blood sugar levels in individuals with diabetes.
Glypride 2 MG Tablets work by employing the active ingredient glimepiride, a sulfonylurea, to influence the regulation of blood sugar levels in individuals with type 2 diabetes mellitus. The medication exerts its effects through a specific mechanism of action:
1. Stimulation of Insulin Release:
Target: Pancreatic Beta Cells
Glimepiride, the active compound in Glypride 2 MG Tablets, acts on the pancreatic beta cells located in the Islets of Langerhans.
2. Interaction with Sulfonylurea Receptors:
Target: Sulfonylurea Receptors on Beta Cells
Glimepiride binds to specific receptors known as sulfonylurea receptors on the pancreatic beta cells.
3. Closure of ATP-Sensitive Potassium Channels:
Result: Inhibition of Potassium Efflux
Upon binding, glimepiride inhibits the ATP-sensitive potassium channels on the beta cell membrane.
This inhibition prevents the efflux of potassium ions from the beta cells.
4. Membrane Depolarization:
Result: Membrane Becomes Depolarized
The closure of potassium channels leads to the depolarization of the beta cell membrane.
5. Calcium Influx into Beta Cells:
Result: Increased Intracellular Calcium Levels
Membrane depolarization triggers an influx of calcium ions into the beta cells.
6. Insulin Secretion:
Result: Release of Insulin into Bloodstream
The increased intracellular calcium levels stimulate the release of insulin from the pancreatic beta cells into the bloodstream.
7. Enhanced Glucose Uptake:
Result: Improved Cellular Glucose Uptake
The released insulin facilitates the uptake of glucose by cells, especially in muscle and adipose tissue.
This increased cellular glucose uptake reduces the concentration of glucose in the bloodstream.
8. Decreased Hepatic Glucose Production:
Result: Inhibition of Glucose Production by the Liver
Glimepiride also suppresses the hepatic (liver) production of glucose, contributing to overall blood sugar control.
Active Ingredient:
Glimepiride (2 mg):
Glimepiride is the primary active ingredient in Glypride 2 MG Tablets. It belongs to the sulfonylurea class of medications and plays a key role in regulating blood sugar levels in individuals with type 2 diabetes.
Dosage:
The standard dosage of Glypride 2 MG Tablets is determined by the healthcare provider based on the individual's medical condition, response to treatment, and other relevant factors.
The usual starting dose may be adjusted over time to achieve optimal blood sugar control.
It is typically taken orally with the first main meal of the day, such as breakfast.
Here's a breakdown of who can use Glypride 2 MG Tablets:
Type 2 Diabetes Patients:
Eligibility: Individuals diagnosed with type 2 diabetes mellitus.
Reasoning: Glypride 2 MG Tablets are designed to help manage blood sugar levels in people with type 2 diabetes, particularly when lifestyle modifications alone are insufficient.
Adults:
Eligibility: Typically prescribed for adults.
Reasoning: The safety and efficacy of Glypride 2 MG Tablets in pediatric populations may not be well-established. Therefore, it is generally reserved for use in adults.
Prescription-Based:
Eligibility: Individuals with a valid prescription from a healthcare provider.
Reasoning: Glypride 2 MG Tablets are prescription medications, and their use should be initiated and monitored under the guidance of a qualified healthcare professional.
Not for Type 1 Diabetes:
Ineligibility: Individuals with type 1 diabetes.
Reasoning: Glypride 2 MG Tablets are not indicated for type 1 diabetes, which is characterized by a lack of insulin production. The mechanism of action of this medication is primarily based on enhancing insulin secretion.
Assessment of Health Status:
Eligibility: Determined based on an individual's overall health status and medical history.
Reasoning: The healthcare provider assesses various factors, such as existing medical conditions, allergies, and potential drug interactions, to determine if Glypride 2 MG Tablets are a suitable choice.
Individualized Treatment:
Eligibility: Determined based on individual response to treatment.
Reasoning: Glypride 2 MG Tablets may be part of an individualized treatment plan. Dosages and treatment strategies are often tailored to the specific needs and responses of each patient.
Avoidance in Pregnancy and Breastfeeding:
Ineligibility: Pregnant or breastfeeding women.
Reasoning: Glypride 2 MG Tablets may not be recommended during pregnancy or breastfeeding, and alternative approaches are typically considered. Women in these conditions should consult their healthcare provider for appropriate guidance.
Skipping Doses
Double Dosing
Inconsistent Timing
Ignoring Lifestyle Modifications
Overlooking Regular Monitoring
Not Reporting Side Effects
Alcohol Overconsumption
Self-Adjusting Dosages
Not Seeking Professional Advice
Ignoring Hypoglycemia Symptoms
Discontinuing Medication Abruptly
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Q: What is Glypride 2 MG Tablets used for?
A: Glypride 2 MG Tablets are used for the management of type 2 diabetes mellitus. The active ingredient, glimepiride, helps control blood sugar levels in individuals with this condition.
Q: How does Glypride 2 MG Tablets work?
A: Glypride 2 MG Tablets work by stimulating the release of insulin from the pancreas. This helps facilitate the uptake of glucose by cells, reducing elevated blood sugar levels.
Q: What is the recommended dosage of Glypride 2 MG Tablets?
A: The recommended dosage is determined by your healthcare provider based on your individual medical condition and response to treatment. It is typically taken once daily with the first main meal of the day.
Q: Can Glypride 2 MG Tablets be taken with other diabetes medications?
A: Your healthcare provider may prescribe Glypride 2 MG Tablets alone or in combination with other antidiabetic medications, depending on your specific needs.
Q: Are there any dietary restrictions while taking Glypride 2 MG Tablets?
A: It's advisable to follow a balanced and healthy diet. Your healthcare provider may provide dietary recommendations to complement the medication.
Q: Can Glypride 2 MG Tablets cause low blood sugar (hypoglycemia)?
A: Yes, Glypride 2 MG Tablets can lower blood sugar levels, and hypoglycemia may occur. It's important to monitor your blood sugar regularly, be aware of symptoms, and follow your healthcare provider's guidance.
Q: What should I do if I miss a dose of Glypride 2 MG Tablets?
A: If you miss a dose, take it as soon as you remember. However, if it's close to the next scheduled dose, skip the missed one. Avoid doubling up on doses.
Q: Can Glypride 2 MG Tablets be taken during pregnancy?
A: Inform your healthcare provider if you are pregnant or planning to become pregnant. They will assess the benefits and risks and may adjust the treatment plan accordingly.
Q: What are the common side effects of Glypride 2 MG Tablets?
A: Common side effects may include hypoglycemia, nausea, dizziness, headache, increased sensitivity to sunlight, skin reactions, and weight gain. Report persistent or severe side effects to your healthcare provider.
Q: Is alcohol consumption safe while taking Glypride 2 MG Tablets?
A: It's advisable to limit alcohol consumption while taking Glypride 2 MG Tablets, as alcohol can interact with the medication and increase the risk of hypoglycemia.
Q: Can Glypride 2 MG Tablets be used in children?
A: The safety and efficacy of Glypride 2 MG Tablets in pediatric populations may not be well-established. It is typically prescribed for adults.
Q: How often should I have my blood sugar levels checked while taking Glypride 2 MG Tablets?
A: Your healthcare provider will determine the frequency of blood sugar monitoring based on your individual needs. Regular monitoring helps assess the effectiveness of the medication.
Common side effects of Glypride 2 MG Tablets may include:
Hypoglycemia (Low Blood Sugar)
Nausea
Dizziness
Headache
Skin Reactions
Weight Gain
Here are the primary uses of Glypride 2 MG Tablets:
Blood Sugar Control:
Purpose: The fundamental use of Glypride 2 MG Tablets is to regulate and control blood sugar levels in individuals diagnosed with type 2 diabetes.
How it Works: The active ingredient, glimepiride, stimulates the release of insulin from the pancreas, facilitating the uptake of glucose by cells and reducing elevated blood glucose levels.
Improved Insulin Sensitivity:
Purpose: Glypride 2 MG Tablets contribute to increased insulin sensitivity.
How it Works: By enhancing the body's response to insulin, the medication aids in more effective utilization of glucose by cells, helping to maintain blood sugar within the target range.
Adjunct to Lifestyle Modifications:
Purpose: Glypride 2 MG Tablets are often prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications.
How it Works: Lifestyle changes, such as adopting a healthy diet and engaging in regular physical activity, combined with medication, can contribute to better blood sugar control.
Prevention of Complications:
Purpose: By maintaining optimal blood sugar levels, Glypride 2 MG Tablets may contribute to the prevention or delay of diabetes-related complications.
How it Works: Controlling blood glucose helps reduce the risk of complications such as cardiovascular disease, kidney problems, and nerve damage associated with diabetes.
Individualized Treatment:
Purpose: Glypride 2 MG Tablets are often part of an individualized treatment plan.
How it Works: Dosages and treatment strategies are tailored to each patient's specific needs, considering factors such as overall health, response to treatment, and potential side effects.
Combination Therapy:
Purpose: Glypride 2 MG Tablets may be used alone or in combination with other antidiabetic medications.
How it Works: Combining medications with different mechanisms of action can provide synergistic effects, enhancing overall blood sugar control.
Support for Lifestyle Changes:
Purpose: Glypride 2 MG Tablets can support individuals in making and sustaining lifestyle changes.
How it Works: The medication complements efforts to adopt a healthy lifestyle by assisting in blood sugar management, making it a valuable component of a holistic approach to diabetes care.
1. Prescription and Dosage:
Glypride 2 MG Tablets are prescription medications. Obtain them only with a valid prescription from your healthcare provider.
The dosage is determined by your healthcare provider based on your medical condition, response to treatment, and other relevant factors.
2. Timing of Administration:
Take Glypride 2 MG Tablets as directed by your healthcare provider.
The usual recommendation is to take the tablet with the first main meal of the day, often with breakfast.
3. Oral Administration:
Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet unless advised otherwise by your healthcare provider.
4. Regular Schedule:
Take Glypride 2 MG Tablets at the same time each day.
Establishing a consistent routine helps maintain stable blood sugar levels.
5. Follow Healthcare Provider's Instructions:
Adhere to your healthcare provider's instructions regarding dosage adjustments, especially if changes are made during the course of treatment.
6. Missed Dose:
If you miss a dose, take it as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule.
Do not double up on doses to make up for a missed one.
7. Regular Monitoring:
Regularly monitor your blood sugar levels as advised by your healthcare provider.
Keep track of any changes or patterns in your blood sugar readings.
8. Lifestyle Modifications:
Glypride 2 MG Tablets work effectively when complemented by lifestyle modifications.
Follow a healthy diet, engage in regular physical activity, and manage stress to enhance overall diabetes management.
9. Blood Tests:
Your healthcare provider may recommend periodic blood tests to assess the effectiveness of the medication and ensure that your blood sugar levels are within the target range.
10. Consultation with Healthcare Provider:
Inform your healthcare provider of any changes in your health, medication side effects, or concerns related to Glypride 2 MG Tablets.
Do not make any adjustments to your medication without consulting your healthcare provider.
11. Precautions:
Avoid excessive alcohol consumption while taking Glypride 2 MG Tablets, as it may potentiate the risk of hypoglycemia (low blood sugar).
Follow your healthcare provider's advice on managing hypoglycemia, including the use of glucose sources if needed.
12. Storage:
Store Glypride 2 MG Tablets according to the instructions provided, away from excessive heat or moisture.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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