Generic Name : Nexavar
Brand Name : Sorafenib
Manufacturer Name : Cipla India
Product Code : OBP 932
Delivery Days : 10 To 12 Working Days
Composition : Nexavar
Strength : 200mg
Packaging : Tablet (Blisters)
Presentation : Pills Strip
Drug Class : Angiogenesis Inhibitor
Prescribed For : Used to treat kidney cancer
Side Effects : Fatigue, Nausea, Loss of appetite, Diarrhea, Abdominal pain, Hair loss, Weight loss, Rash
| Pack Size/Qty | Price | Price Per Pill or unit | |
| 240 TABLET'S | $357.60 | $1.49 | |
| 120 TABLET'S | $181.20 | $1.51 |
Soranib 200 MG Tablet is a medication that contains the active ingredient Sorafenib. It is classified as a kinase inhibitor, which is a type of targeted therapy used in the treatment of certain types of cancer. Soranib is specifically designed to inhibit the activity of various proteins and receptors involved in the growth and spread of cancer cells.
Here's how Soranib works:
Inhibition of Kinases:
Sorafenib selectively inhibits several kinases, which are enzymes that play a crucial role in cell signaling and growth. By doing so, it interferes with the signaling pathways that promote the proliferation and survival of cancer cells.
Angiogenesis Inhibition:
Cancer tumors require a blood supply to grow and spread. Soranib inhibits angiogenesis, the formation of new blood vessels, by targeting vascular endothelial growth factor receptors (VEGFR). This helps to deprive the tumor of the nutrients and oxygen it needs for sustained growth.
Raf/MAPK Pathway Inhibition:
Sorafenib interferes with the Raf/MAPK signaling pathway, which is involved in regulating cell division and survival. By disrupting this pathway, the medication hinders the uncontrolled growth of cancer cells.
PDGFR Inhibition:
Soranib also inhibits platelet-derived growth factor receptors (PDGFR), which are involved in cell growth and division. Inhibition of PDGFR contributes to the overall anti-cancer effects of the medication.
Apoptosis Induction:
Apoptosis, or programmed cell death, is a natural process that eliminates damaged or unwanted cells. Soranib promotes apoptosis in cancer cells, contributing to the reduction of tumor size and progression.
Ingredients:
The active ingredient in Soranib 200 MG Tablet is Sorafenib. Each tablet contains 200 milligrams of Sorafenib.
Dosage:
The dosage of Soranib 200 MG Tablet is determined by the healthcare provider based on various factors, including the type of cancer being treated, the individual's overall health, and the specific treatment plan. It is crucial for patients to follow the prescribed dosage and administration instructions provided by their oncologist.
Typically, Soranib is taken orally with water, and the tablets are swallowed whole without crushing or chewing.
The frequency of administration and the duration of treatment cycles are also determined by the healthcare provider. Soranib treatment may involve continuous use or intermittent cycles, depending on the response to therapy.
Dosage adjustments may be made by the healthcare provider based on the individual's tolerance to the medication and any observed side effects.
Patients should not alter the dosage or discontinue the medication without consulting their healthcare provider. If a dose is missed, patients are usually advised to take it as soon as they remember, but they should not double up on doses to make up for a missed one.
Here are general considerations for individuals who may use Soranib 200 MG Tablet:
Indications:
Renal Cell Carcinoma (Kidney Cancer):
Soranib is often prescribed for the treatment of advanced renal cell carcinoma, a type of kidney cancer. It may be recommended when the cancer is not amenable to surgical removal.
Hepatocellular Carcinoma (Liver Cancer):
Soranib is also used in the treatment of hepatocellular carcinoma, which is a primary form of liver cancer. It may be prescribed for advanced cases where surgical intervention is not a viable option.
Considerations for Use:
Medical Evaluation:
The decision to use Soranib 200 MG Tablet is based on a comprehensive medical evaluation by an oncologist. The healthcare provider considers factors such as the type and stage of cancer, the individual's overall health, and the potential benefits and risks of the treatment.
Liver and Kidney Function:
Individuals using Soranib undergo assessments of liver and kidney function before and during treatment. This is to ensure that the medication is safe and well-tolerated.
Other Treatment Options:
Soranib may be considered when other treatment options, such as surgery or traditional chemotherapy, are not suitable or have not provided the desired outcomes.
Monitoring and Follow-Up:
Regular monitoring and follow-up appointments are essential during Soranib treatment. This helps healthcare providers assess the response to therapy, make any necessary dosage adjustments, and manage potential side effects.
Contraindications:
There are specific contraindications and precautions associated with Soranib. For example, individuals with certain pre existing medical conditions or allergies may not be suitable candidates. Pregnant or breastfeeding individuals may also need special considerations.
Skipping Doses:
Avoid skipping doses of Soranib. Consistency in taking the medication as prescribed is crucial for the effectiveness of the treatment. If you miss a dose, follow the instructions provided by your healthcare provider.
Altering Dosage Without Consultation:
Do not alter the dosage or frequency of Soranib without consulting your healthcare provider. Changes to the treatment plan should only be made under their guidance.
Crushing or Chewing the Tablet:
Soranib tablets should be swallowed whole with water. Do not crush, chew, or break the tablet, as this may affect the controlled release of the medication.
Not Reporting Side Effects:
If you experience any side effects or unusual symptoms, do not ignore them. Report these to your healthcare provider promptly. They can provide guidance on managing side effects or adjust the treatment plan if necessary.
Inconsistent Timing of Medication:
Try to take Soranib at the same time each day. Inconsistent timing may affect the concentration of the drug in your body and its therapeutic efficacy.
Not Attending Follow-Up Appointments:
Regular follow-up appointments are essential for monitoring your response to Soranib and managing any potential side effects. Avoid missing these appointments.
Not Informing Healthcare Provider of Other Medications:
Inform your healthcare provider about all medications, including over-the-counter drugs, supplements, and herbal products you are taking. Some substances may interact with Soranib.
Not Following Dietary Instructions:
Your healthcare provider may provide specific dietary instructions. Follow these, as they may help manage side effects and optimize the effectiveness of Soranib.
Ignoring Pregnancy and Contraception Discussions:
If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. Suitable contraceptive measures may be recommended to avoid potential harm to the fetus.
Self-Adjusting Treatment Plan:
Do not make changes to your treatment plan on your own. If you have concerns or considerations, discuss them with your healthcare provider, who can make informed decisions based on your individual health status.
Neglecting to Stay Hydrated:
Soranib may cause side effects such as diarrhea. Ensure you stay adequately hydrated to manage gastrointestinal symptoms. Consult your healthcare provider if these symptoms persist.
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1. What is the Soranib 200 MG Tablet used for?
Soranib is used for the treatment of advanced renal cell carcinoma (kidney cancer) and hepatocellular carcinoma (liver cancer) when surgical removal is not feasible.
2. How does Soranib work?
Soranib is a kinase inhibitor that interferes with multiple signaling pathways involved in the growth and spread of cancer cells. It inhibits angiogenesis, disrupts cell proliferation pathways, and induces apoptosis (programmed cell death).
3. How should I take Soranib 200 MG Tablet?
Take Soranib as prescribed by your healthcare provider. Swallow the tablet whole with water, and do not crush or chew it. Follow your provider's instructions on timing and whether to take it with or without food.
4. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one. Do not double up on doses to make up for a missed one.
5. What are the common side effects of Soranib?
Common side effects include fatigue, diarrhea, hand-foot skin reaction, high blood pressure, nausea, loss of appetite, hair changes, voice changes, bleeding or bruising, headaches, joint pain, rash, weakness, and difficulty breathing.
6. How often will I need to see my healthcare provider during Soranib treatment?
Regular follow-up appointments are essential to monitor your response to treatment and manage any side effects. Your healthcare provider will determine the frequency of these visits.
7. Can Soranib be taken during pregnancy or breastfeeding?
Soranib may cause harm to the fetus, and its use during pregnancy is generally not recommended. Effective contraception is advised during treatment. Breastfeeding is also not recommended due to potential risks.
8. Can I take other medications or supplements while on Soranib?
Inform your healthcare provider about all medications, supplements, and herbal products you are taking. Some substances may interact with Soranib, and adjustments may be needed.
9. Can I consume alcohol while on Soranib?
It's advisable to discuss alcohol consumption with your healthcare provider. Alcohol may interact with medications and can have additional effects on the liver.
10. How long will I need to take Soranib?
The duration of Soranib treatment is determined by your healthcare provider based on the type and stage of cancer and your individual response to the medication.
11. Are there any specific dietary restrictions with Soranib?
Your healthcare provider may provide dietary recommendations to manage side effects. Follow these instructions, and stay well-hydrated, especially if diarrhea occurs.
Fatigue:
Feeling tired or experiencing a lack of energy is a common side effect of Soranib. Get adequate rest and inform your healthcare provider if fatigue persists.
Diarrhea:
Soranib may cause diarrhea. Stay well-hydrated and follow dietary recommendations provided by your healthcare provider. If diarrhea is severe or persistent, seek medical advice.
Hand-Foot Skin Reaction:
Some individuals may develop redness, swelling, or tenderness on the palms of the hands and soles of the feet. Moisturize your skin and avoid exposure to extreme temperatures. Report any skin changes to your healthcare provider.
Hypertension (High Blood Pressure):
Soranib can lead to an increase in blood pressure. Regular blood pressure monitoring and appropriate management will be recommended by your healthcare provider.
Nausea:
Feeling nauseous or experiencing an upset stomach is a common side effect. Follow dietary recommendations, and inform your healthcare provider if nausea persists.
Loss of Appetite:
Some individuals may experience a decrease in appetite while taking Soranib. Maintaining a balanced diet is important. Consult your healthcare provider if appetite loss is a concern.
Hair Changes:
Hair thinning or changes in hair texture may occur. These changes are usually reversible after completion of treatment.
Voice Changes:
Soranib may cause changes in your voice, such as hoarseness. If this persists or becomes bothersome, inform your healthcare provider.
Bleeding or Bruising:
Soranib may affect blood clotting. Inform your healthcare provider if you notice unusual bleeding or bruising.
Headache:
Headaches may occur as a side effect. If headaches are severe or persistent, inform your healthcare provider.
Joint Pain:
Some individuals may experience joint pain. Inform your healthcare provider if joint pain becomes bothersome.
Rash:
Skin rash or irritation may occur. If you notice a rash, report it to your healthcare provider for guidance.
Weakness:
Feeling weak or experiencing muscle weakness is a possible side effect. If weakness persists, consult your healthcare provider.
Difficulty Breathing:
In rare cases, Soranib may cause difficulty breathing. Seek immediate medical attention if you experience shortness of breath or respiratory distress.
Soranib 200 MG Tablet is used for the treatment of specific types of cancer, and its primary indications include:
Renal Cell Carcinoma (Kidney Cancer):
Soranib is used in the treatment of advanced renal cell carcinoma, a type of kidney cancer. It may be prescribed when the cancer has spread beyond the kidney or when surgical removal is not a feasible option.
Hepatocellular Carcinoma (Liver Cancer):
Soranib is indicated for the treatment of hepatocellular carcinoma, the most common form of primary liver cancer. It is often prescribed for cases where surgical intervention is not a suitable option, and the cancer is advanced or has metastasized.
Dosage and Administration:
Take Soranib 200 MG Tablet exactly as prescribed by your healthcare provider. Do not alter the dosage without consulting your doctor.
Oral Administration:
Soranib is usually taken orally with a glass of water. Swallow the tablet whole without crushing, chewing, or breaking it.
Timing of Administration:
Take Soranib either with or without food, as directed by your healthcare provider. Follow the specific instructions provided to you.
Regular Schedule:
Take the medication at the same time each day to maintain a consistent level of the drug in your body.
Missed Dose:
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Do not double up on doses to make up for a missed one.
Do Not Alter the Tablet:
Do not crush, chew, or break the tablet. Swallow it whole.
Follow-up Appointments:
Attend all scheduled follow-up appointments with your healthcare provider. These visits are important for monitoring your response to treatment and managing any potential side effects.
Compliance:
Adhere to the prescribed treatment plan consistently. If you have any concerns about the medication or experience side effects, discuss them with your healthcare provider before making any changes.
Precautions:
Follow any additional precautions or instructions provided by your healthcare provider. Inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with Soranib.
Pregnancy and Breastfeeding:
If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. Soranib may have implications for fetal development, and suitable contraceptive measures may be recommended.
Symptoms and Side Effects:
Be vigilant for any unusual symptoms or side effects, and report them to your healthcare provider promptly.
The information provided on website is intended for educational purposes only and should not be used as a substitute for professional medical advice. Please consult a qualified healthcare professional for personalized medical advice.
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